Title:
METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND
Document Type and Number:
WIPO Patent Application WO/2022/014414
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a method for more efficiently producing specific optically active compounds including optically active 1-acetyl-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline. The present invention provides a method for producing an optically active compound represented by formula (3) (wherein R5 represents a hydrogen atom, etc., R6 and R7 each independently represent a hydrogen atom, etc., R8 represents a C1-C6 alkyl group, R9, R10, and R11 each independently represent a hydrogen atom, etc., and the asterisked carbon atom is an asymmetric carbon atom), the method comprising reacting a compound represented by formula (2) (wherein R5, R6, R7, R8, R9, R10, and R11 respectively have the same meanings as defined above) with hydrogen in the presence of an asymmetric cobalt complex.
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Inventors:
LUTETE LEOPOLD MPAKA (JP)
HAGIYA KOJI (JP)
HAGIYA KOJI (JP)
Application Number:
PCT/JP2021/025489
Publication Date:
January 20, 2022
Filing Date:
July 06, 2021
Export Citation:
Assignee:
SUMITOMO CHEMICAL CO (JP)
International Classes:
C07B53/00; B01J31/22; C07B61/00; C07C209/62; C07C211/60; C07C231/12; C07C233/07; C07D215/08; C07D231/14; C07F15/06
Domestic Patent References:
| WO2015141564A1 | 2015-09-24 | |||
| WO2013086397A1 | 2013-06-13 | |||
| WO2015141564A1 | 2015-09-24 | |||
| WO2011162397A1 | 2011-12-29 | |||
| WO2015118793A1 | 2015-08-13 | |||
| WO2015141564A1 | 2015-09-24 |
Foreign References:
| JPH07215921A | 1995-08-15 | |||
| JP2012025735A | 2012-02-09 | |||
| JP2018039757A | 2018-03-15 | |||
| JPH07215921A | 1995-08-15 |
Other References:
GUO JUN, LU ZHAN: "Highly Chemo-, Regio-, and Stereoselective Cobalt-Catalyzed Markovnikov Hydrosilylation of Alkynes", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, ¬VERLAG CHEMIE| :, vol. 55, no. 36, 26 August 2016 (2016-08-26), pages 10835 - 10838, XP055899787, ISSN: 1433-7851, DOI: 10.1002/anie.201605501
ZUO ZIQING, YANG JI, HUANG ZHENG: "Cobalt-Catalyzed Alkyne Hydrosilylation and Sequential Vinylsilane Hydroboration with Markovnikov Selectivity", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 55, no. 36, 26 August 2016 (2016-08-26), pages 10839 - 10843, XP055899789, ISSN: 1433-7851, DOI: 10.1002/anie.201605615
J. AMER. CHEM. SOC., vol. 134, 2012, pages 4561 - 4564
ANGEW. CHEM. INT. ED., vol. 55, 2016, pages 10839
TETRAHEDRON LETTERS, vol. 45, 2004, pages 8988
J. CHEM. SOC. (C, 1966, pages 514
APPLIED CATALYSIS A: GENERAL, vol. 492, 2015, pages 252 - 261
ZUO ZIQING, YANG JI, HUANG ZHENG: "Cobalt-Catalyzed Alkyne Hydrosilylation and Sequential Vinylsilane Hydroboration with Markovnikov Selectivity", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 55, no. 36, 26 August 2016 (2016-08-26), pages 10839 - 10843, XP055899789, ISSN: 1433-7851, DOI: 10.1002/anie.201605615
J. AMER. CHEM. SOC., vol. 134, 2012, pages 4561 - 4564
ANGEW. CHEM. INT. ED., vol. 55, 2016, pages 10839
TETRAHEDRON LETTERS, vol. 45, 2004, pages 8988
J. CHEM. SOC. (C, 1966, pages 514
APPLIED CATALYSIS A: GENERAL, vol. 492, 2015, pages 252 - 261
Attorney, Agent or Firm:
NAKAYAMA, Tohru et al. (JP)
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