METHOD FOR PURIFYING ANTIBODY

WIPO Patent Application WO/2024/058110

A1

This method for purifying an antibody comprises preparing a solution containing an antibody, and filtering the solution using a porous membrane containing regenerated cellulose to purify the antibody. This method for purifying an antibody comprises preparing a solution containing an antibody, and filtering the solution using a porous membrane containing regenerated cellulose to purify the antibody, wherein: (A) Tr-Tm of the antibody in hydrophobic interaction chromatography is not less than 15 min; and/or (B) the k value of the antibody in hydrophobic interaction chromatography is not less than 19.

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HIDAKA JUNJI (JP)
TANIGUCHI HIROKI (JP)
FUTAMURA AKIKA (JP)

PCT/JP2023/033020

March 21, 2024

September 11, 2023

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ASAHI KASEI MEDICAL CO LTD (JP)

C07K1/34; C07K16/00; C12P21/08

WO2022118943A1

2022-06-09

JP2018510166A	2018-04-12
JPH06279296A	1994-10-04
JP2003012693A	2003-01-15
US20180028593A1	2018-02-01

TOMOKO HONGO‐HIRASAKI; MASAYASU KOMURO; SHOICHI IDE: "Effect of antibody solution conditions on filter performance for virus removal filter Planova™ 20N", BIOTECHNOLOGY PROGRESS, AMERICAN CHEMICAL SOCIETY, HOBOKEN, USA, vol. 26, no. 4, 2 March 2010 (2010-03-02), Hoboken, USA, pages 1080 - 1087, XP072293148, ISSN: 8756-7938, DOI: 10.1002/btpr.415

INABA, Yoshiyuki et al. (JP)

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