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Title:
METHODS FOR APOLIPOPROTEIN DETECTION
Document Type and Number:
WIPO Patent Application WO/2017/076919
Kind Code:
A3
Abstract:
The present invention relates to methods for the detection and quantification of apolipoproteins and isoforms thereof in a sample, as well as to predictive methods of the probability of neurodegenerative or cardiovascular disease development based on apolipoprotein levels as determined by the detection methods of the invention.

Inventors:
RODRÍGUEZ MARTÍN ANDRÉS (ES)
CALERO LARA MIGUEL (ES)
CALERO RUEDA M OLGA (ES)
GARCÍA ALBERT LUIS (ES)
Application Number:
PCT/EP2016/076457
Publication Date:
June 15, 2017
Filing Date:
November 02, 2016
Export Citation:
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Assignee:
BIOCROSS S L (ES)
INST DE SALUD CARLOS III (ES)
CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED DE ENFERMEDADES NEURODEGENERATIVAS (ES)
International Classes:
G01N33/92; G01N33/68
Domestic Patent References:
WO2011109246A12011-09-09
WO2000055635A12000-09-21
Other References:
C. Y. D. LEE ET AL: "Apolipoprotein E Promotes -Amyloid Trafficking and Degradation by Modulating Microglial Cholesterol Levels", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 287, no. 3, 13 January 2012 (2012-01-13), US, pages 2032 - 2044, XP055261606, ISSN: 0021-9258, DOI: 10.1074/jbc.M111.295451
DAVID B POLIS ET AL: "ISOLATION OF A CRYSTALLINE ALBUMIN FROM MILK*", J BIOL CHEM, vol. 187, 1 November 1950 (1950-11-01), pages 349 - 354, XP055347922
Attorney, Agent or Firm:
ALCONADA RODRIGUEZ, Agustín (ES)
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