METHODS AND COMPOSITIONS FOR THE TREATMENT OF LIPID-ASSOCIATED DISORDERS

Title:

METHODS AND COMPOSITIONS FOR THE TREATMENT OF LIPID-ASSOCIATED DISORDERS

Document Type and Number:

WIPO Patent Application WO2006089009

Kind Code:

A8

Abstract:

The invention provides a method of identifying a niacin receptor modulator with reduced flushing effect compared to niacin or a niacin analog, comprising determining the MAP kinase activity of said modulator, wherein a decrease in MAP kinase activity induced by said modulator compared to MAP kinase activity induced by niacin or a niacin analog indicates that said modulator has reduced flushing effect when compared to niacin or a niacin analog.

More Like This:

JP2007521015	Differentially expressed tumor-specific polypeptides used in the diagnosis and treatment of cancer
JP3964374	ACRIDINIUM COMPOUNDS IN HOMOGENEOUS SYSTEM ASSAY AND NEW APPLICATION OF DERIVATIVES
WO/2002/040681	THE POLYPEPTIDE FRAGMENTS OF HEPATITIS E VIRUS, THE VACCINE COMPOSITION COMPRISING SAID FRAGMENTS AND THE DIAGNOSTIC KITS

Inventors:

KANEMITSU-PARKS MARTHA (US)
RICHMAN JEREMY G (US)
MACIEJEWSKI-LENOIR DOMINIQUE (US)
CONNOLLY DANIEL T (US)

Application Number:

PCT/US2006/005450

Publication Date:

October 04, 2007

Filing Date:

February 18, 2006

Export Citation:

Click for automatic bibliography generation Help

Assignee:

ARENA PHARM INC (US)
KANEMITSU-PARKS MARTHA (US)
RICHMAN JEREMY G (US)
MACIEJEWSKI-LENOIR DOMINIQUE (US)
CONNOLLY DANIEL T (US)

International Classes:

G01N33/566; A61K31/443

Download PDF:

View/Download PDF PDF Help

Previous Patent: PROCESSES FOR THE 3,3-DIALKYLATION OF 4-CHROMANONES

Next Patent: COMPRESSION TOOL JAW SET