NOVEL BETA-TUBULIN PROTEIN OF CANDIDA GLABRATA AND METHODS FOR ITS USE

Title:

NOVEL BETA-TUBULIN PROTEIN OF CANDIDA GLABRATA AND METHODS FOR ITS USE

Document Type and Number:

WIPO Patent Application WO2004092328

Kind Code:

A3

Abstract:

The present invention provides isolated nucleic acid and amino acid sequences of Candida glabrata beta-tubulin, antibodies to C. glabrata beta-tubulin, and methods of screening to identify antifungals using biologically active C. glabrata beta-tubulin.

Inventors:

MAXON MARY (US)
CLARKE DAVID (US)
BERAUD CHRISTOPHE (US)

Application Number:

PCT/US2004/010604

Publication Date:

October 13, 2005

Filing Date:

April 08, 2004

Export Citation:

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Assignee:

CYTOKINETICS INC (US)
MAXON MARY (US)
CLARKE DAVID (US)
BERAUD CHRISTOPHE (US)

International Classes:

C07H21/04; C07K14/40; (IPC1-7): C12N3/00; C12N1/00; C12N1/12; G01N33/569

Domestic Patent References:

WO1992003455A1

1992-03-05

Other References:

FIDEL P.L. ET AL: "Candida glabrata: Reviews of Epidemiology, Pathogenesis and Clinical Disease with Comparison of C. albicans.", vol. 12, no. 1, January 1999 (1999-01-01), pages 80 - 96, XP002988992

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