PHARMACEUTICAL COMPOSITION COMPRISING A 5HT1 RECEPTOR AGONIST

WIPO Patent Application WO2003047552

A3

The present invention relates to a pharmaceutical composition for oral administration capable of rapid disintegration and dispersion within the gastrointestinal tract comprising a 5HT1 receptor agonist as active ingredient, in particular a composition in solid-dosage form that is intended to be swallowed, and methods of treatment of cephalic pain, especially migraine, using such composition.

BAKER ROBERT WILLIAM (GB)
DOW ALAN DAVID (GB)
SUMMERS SIMON JOHN (GB)
WESTRUP JULIAN (GB)

PCT/EP2002/013715

September 25, 2003

December 04, 2002

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GLAXO GROUP LTD (GB)
BAKER ROBERT WILLIAM (GB)
DOW ALAN DAVID (GB)
SUMMERS SIMON JOHN (GB)
WESTRUP JULIAN (GB)

A61K9/20; A61K9/22; A61K9/28; A61K9/46; A61K31/00; A61K31/40; A61K31/404; A61K31/4045; A61K31/4172; A61K47/04; A61K47/38; A61P25/04; A61P25/06; A61P43/00; (IPC1-7): A61K9/22; A61K9/46; A61K31/00

WO2001080822A2	2001-11-01
WO1999043306A1	1999-09-02
WO1992011003A1	1992-07-09
WO1992015295A1	1992-09-17
WO1998042344A1	1998-10-01
WO2001039836A1	2001-06-07
WO2001089485A1	2001-11-29

ANONYMOUS: "Zomig-ZMT(TM) Orally Disintegrating Tablets", INTERNET ARTICLE, 12 February 2001 (2001-02-12), XP002241488, Retrieved from the Internet [retrieved on 20030515]
AHRENS S P ET AL: "Efficacy and safety of rizatriptan wafer for the acute treatment of migraine.", CEPHALALGIA, vol. 19, no. 5, June 1999 (1999-06-01), pages 525 - 530, XP002241489, ISSN: 0333-1024

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