PHARMACEUTICAL COMPOSITION, METHOD FOR STABILISNG PHARMACEUTICAL COMPOSITION, AND METHOD FOR EVALUATING STORAGE STABILITY OF PHARMACEUTICAL COMPOSITION

WIPO Patent Application WO/2019/088274

A1

Provided is a pharmaceutical composition that exhibits superior storage stability even if mixed with a high concentration of L-menthol. The pharmaceutical composition comprises a component (A), a component (B), a component (C), a component (D) and a component (E) as detailed hereinafter, and has a cloud point of 30–75°C. Component (A): L-menthol. Component (B): At least one substance selected from the group consisting of medium-chain fatty-acid triglycerides, medium-chain fatty acids and salts of medium-chain fatty acids. Component (C): A nonionic surfacant having a HLB of at least 10. Component (D): A polyhydric alcohol comprising at least three hydroxl groups within a molecule; and/or a poly(oxyalkylene) glycol. Component (E): Water.

WO/2005/097091	COMPOSITION COMPRISING REDUCED-FORM COENZYME Q10 AND CAROTENOID COMPOUND
WO/1999/062500	STABILIZERS FOR LYOPHILIZED VACCINES
JP2000159678	OINTMENT PREPARATION

HAMAWAKI TOMONORI (JP)
OIZUMI KUMIKO (JP)
IWASAKI NORIYUKI (JP)

PCT/JP2018/040921

May 09, 2019

October 30, 2018

Click for automatic bibliography generation  

NIHON PHARMACEUTICAL CO LTD (JP)

A61K31/045; A61K9/107; A61K47/12; A61K47/14; A61K47/26; A61K47/44; A61P1/00

WO2003097027A1	2003-11-27
WO2003097026A1	2003-11-27

JP2005179292A	2005-07-07
JP2001515503A	2001-09-18
JP2009213367A	2009-09-24
JP2001342126A	2001-12-11
JP2017212266A	2017-11-30
JP2017227259A	2017-12-28
JP2003292450A	2003-10-15
JP2005179292A	2005-07-07

See also references of EP 3705119A4

GOTO & CO. (JP)

View/Download PDF      PDF Help

Previous Patent: IMAGE PROCESSING DEVICE, IMAGE PROCESSING METHOD AND IMAGE PROCESSING PROGRAM

Next Patent: CONDUCTIVE MEMBER MODULE, AND PRODUCTION METHOD THEREFOR