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Title:
PHARMACEUTICAL COMPOSITION PARTICLES AND ORALLY DISINTEGRATING PREPARATION INCLUDING SAME
Document Type and Number:
WIPO Patent Application WO/2017/146053
Kind Code:
A1
Abstract:
Provided are: pharmaceutical composition particles and an orally disintegrating tablet including the same which are capable of achieving both the masking of unpalatable taste and an improvement in elution properties; and a method for producing pharmaceutical composition particles. This pharmaceutical composition particle comprises: a core particle including a water-soluble gelling-swelling substance; an intermediate layer that includes a drug and that covers the outer side of the core particle; and an outer layer that includes a water-insoluble substance and that covers the outer side of the intermediate layer. This orally disintegrating tablet comprises said pharmaceutical composition particles.

Inventors:
HAYASHIDA Tomohiro (3023 Nojicho Kusatsu-sh, Shiga 55, 〒5250055, JP)
HOASHI Yohei (3023 Nojicho Kusatsu-sh, Shiga 55, 〒5250055, JP)
IJITSU Shin (3023 Nojicho Kusatsu-sh, Shiga 55, 〒5250055, JP)
NAKANO Yoshio (380, Mita-cho, Kishiwada-sh, Osaka 08, 〒5960808, JP)
YAMAZAKI Junji (380, Mita-cho, Kishiwada-sh, Osaka 08, 〒5960808, JP)
INOUE Katsuhisa (380, Mita-cho, Kishiwada-sh, Osaka 08, 〒5960808, JP)
AIZAWA Atsushi (380, Mita-cho, Kishiwada-sh, Osaka 08, 〒5960808, JP)
Application Number:
JP2017/006389
Publication Date:
August 31, 2017
Filing Date:
February 21, 2017
Export Citation:
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Assignee:
NIPRO CORPORATION (9-3 Honjo-nishi 3-chome, Kita-ku Osaka-sh, Osaka 10, 〒5318510, JP)
ZENSEI PHARMACEUTICAL INDUSTRIES CO.,LTD. (94-2, Hiraoka-cho Nishi-ku, Sakai-sh, Osaka 07, 〒5938307, JP)
International Classes:
A61K47/00; A61K9/14; A61K9/26; A61K31/136; A61K45/00; A61K47/32; A61K47/36; A61K47/38; A61P1/00; A61P1/04; A61P1/06; A61P1/10; A61P1/12; A61P1/14; A61P1/16; A61P3/02; A61P3/06; A61P3/10; A61P5/00; A61P5/38; A61P7/04; A61P7/10; A61P9/00; A61P9/04; A61P9/06; A61P9/10; A61P9/12; A61P11/08; A61P11/10; A61P11/14; A61P11/16; A61P13/00; A61P19/06; A61P19/10; A61P21/00; A61P23/02; A61P25/00; A61P25/06; A61P25/08; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P29/00; A61P31/00; A61P31/04; A61P35/00; A61P37/06; A61P43/00
Foreign References:
JP2004231520A2004-08-19
JP2002212062A2002-07-31
JP2010534203A2010-11-04
JPH10504300A1998-04-28
Attorney, Agent or Firm:
AKAOKA Kazuo et al. (Koei Building 5F, 1-13 Awajimachi 2-chome, Chuo-k, Osaka-shi Osaka 47, 〒5410047, JP)
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