PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING HEPATITIS C VIRUS INFECTIOUS DISEASE - CATHOLIC UNIV KOREA INDUSTRY ACADEMIC COOPERATION FOUNDATION

Title:

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING HEPATITIS C VIRUS INFECTIOUS DISEASE

Document Type and Number:

WIPO Patent Application WO/2015/065020

Kind Code:

A1

Abstract:

The present invention relates to a pharmaceutical composition for preventing or treating hepatitis C virus (HCV) infectious disease. More particularly, the present invention relates to a pharmaceutical composition for preventing or treating HCV infectious disease or an antiviral composition for HCV, containing at least one selected from the group consisting of: GRIM19 protein or a fragment thereof; and a gene encoding the protein or a fragment of the protein.

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Inventors:

YOON SEUNG KEW (KR)
KIM JUNG HEE (KR)
HUR WON HEE (KR)
CHO MI LA (KR)
CHOI JUNG EUN (KR)
LEE EUN BYUL (KR)

Application Number:

PCT/KR2014/010200

Publication Date:

May 07, 2015

Filing Date:

October 28, 2014

Export Citation:

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Assignee:

CATHOLIC UNIV KOREA INDUSTRY ACADEMIC COOPERATION FOUNDATION (KR)

International Classes:

A61K48/00; A61P31/00; A61P31/12

Foreign References:

KR101215670B1

2012-12-26

Other References:

LI F. ET AL.: "Downregulation of GRIM-19 is associated with hyperactivation of p-STAT3 in hepatocellular carcinoma", MED. ONCOL., vol. 29, no. 5, 11 April 2012 (2012-04-11), pages 3046 - 3054
JUN ZHANG ET AL.: "The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3", PNAS, vol. 100, no. 16, 5 August 2003 (2003-08-05), pages 9342 - 9347
KEIGO MACHIDA ET AL.: "c-Jun Mediates Hepatitis C Virus Hepatocarcinogenesis Through Signal Transducer and Activator of Transcription 3 and Nitric Oxide-Dependent Impairment of Oxidative DNA Repair", HEPATOLOGY, vol. 52, no. 2, 2010, pages 480 - 492

Attorney, Agent or Firm:

BAE, KIM & LEE IP GROUP (KR)
특허법인 태평양 (KR)

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