Title:
PREPARATION METHOD OF SUBSTITUTED PYRIMIDINE PIPERAZINE COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2022/057842
Kind Code:
A1
Abstract:
Method for preparation of substituted pyrimidine piperazine compounds, as well as intermediate compounds used in the method. The preparation method provided herein has the advantages of cheap and easily available raw materials, mild conditions, short reaction time, safety and controllability, high total yield, which is especially suitable for industrial production.
Inventors:
JIN CHUANFEI (CN)
LIANG HAIPING (CN)
XU TENGFEI (CN)
ZHANG YINGJUN (CN)
LIANG HAIPING (CN)
XU TENGFEI (CN)
ZHANG YINGJUN (CN)
Application Number:
PCT/CN2021/118629
Publication Date:
March 24, 2022
Filing Date:
September 16, 2021
Export Citation:
Assignee:
SUNSHINE LAKE PHARMA CO LTD (CN)
International Classes:
C07D403/14; C07D417/14
Domestic Patent References:
| WO2019062662A1 | 2019-04-04 |
Foreign References:
| CN103304547A | 2013-09-18 |
Other References:
BIN HU, QIAO SONG, YUNGEN XU: "Scale-Up Synthesis of Antidepressant Drug Vilazodone", ORGANIC PROCESS RESEARCH & DEVELOPMENT, AMERICAN CHEMICAL SOCIETY, vol. 16, no. 9, 21 September 2012 (2012-09-21), pages 1552 - 1557, XP055061951, ISSN: 10836160, DOI: 10.1021/op300171m
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