Title:
PREVENTIVE AND REMEDY FOR HEPATITIS C VIRUS INFECTION
Document Type and Number:
WIPO Patent Application WO/2006/046674
Kind Code:
A1
Abstract:
A medicinal composition for preventing or treating hepatitis C virus infection which contains an extract of a plant belonging to the genus Polygala as the active ingredient. It is preferable that this medicinal composition contains an extract of Onji (root of Polygala Tenuifolia Willdenow) extract or Senega (root of Polygala senega Linne) extract. It is still preferable that the extract comprises a saponin such as onjisaponin or polygala saponin.
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Inventors:
ITO TATSUYA (JP)
AOKI MASAHIRO (JP)
SUDOH MASAYUKI (JP)
AOKI MASAHIRO (JP)
SUDOH MASAYUKI (JP)
Application Number:
PCT/JP2005/019841
Publication Date:
May 04, 2006
Filing Date:
October 21, 2005
Export Citation:
Assignee:
CHUGAI PHARMACEUTICAL CO LTD (JP)
ITO TATSUYA (JP)
AOKI MASAHIRO (JP)
SUDOH MASAYUKI (JP)
ITO TATSUYA (JP)
AOKI MASAHIRO (JP)
SUDOH MASAYUKI (JP)
International Classes:
A61K36/18; A61K31/702; A61K31/704; A61P1/16; A61P31/12; C07H15/256
Domestic Patent References:
| WO1999007395A1 | 1999-02-18 | |||
| WO2000015257A1 | 2000-03-23 |
Foreign References:
| JPH10130162A | 1998-05-19 | |||
| JPH0625003A | 1994-02-01 | |||
| JPH07206694A | 1995-08-08 |
Other References:
NIKAIDO T. ET AL: "Inhibitors of Cyclic Adenosine Monophosphate Phosphodiesterase in Polygala tenuifolia", CHEM. PHARM. BULL., vol. 30, no. 6, 1982, pages 2020 - 2024, XP001094027
ZHANG D. ET AL: "Five New Triterpene Saponins, Polygala yaponica XXVIII-XXXII from the Root of Polygala japonica Houtt", CHEM. PHARM. BULL., vol. 44, no. 4, 1996, pages 810 - 815, XP002995245
ZHANG D. ET AL: "Polygalasaponins XLII-XLVI from Root of Polygala glomerata", PHYTOCHEMISTRY, vol. 47, no. 3, 1998, pages 459 - 466, XP002995246
ZHANG D. ET AL: "Five New Triterpene Saponins, Polygala yaponica XXVIII-XXXII from the Root of Polygala japonica Houtt", CHEM. PHARM. BULL., vol. 44, no. 4, 1996, pages 810 - 815, XP002995245
ZHANG D. ET AL: "Polygalasaponins XLII-XLVI from Root of Polygala glomerata", PHYTOCHEMISTRY, vol. 47, no. 3, 1998, pages 459 - 466, XP002995246
Attorney, Agent or Firm:
Ohno, Seiji (Kasumigaseki Building 36F 2-5, Kasumigaseki
3-chome, Chiyoda-k, Tokyo 36, JP)
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