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Title:
PROCESS FOR PREPARATION OF AMORPHOUS CARVEDILOL PHOSPHATE
Document Type and Number:
WIPO Patent Application WO/2010/092589
Kind Code:
A3
Abstract:
The present invention relates to a process for the preparation of amorphous carvedilol phosphate comprising; adding carvedilol base or carvedilol phosphate to a solvent consisting of water miscible cyclic ether(s) or aliphatic nitrile(s) or a mixture thereof and optionally adding water; optionally, adding orthophosphoric acid or its diluted solution to the preceeding; and spray drying the solution thus obtained to afford amorphous carvedilol phosphate.

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Inventors:
JITENDRA KOUNDINYA (IN)
RAJIV KUMAR (IN)
ASHOK RAMPAL (IN)
DHARMESH KUMAR ARVINDBHAI PATEL (IN)
Application Number:
PCT/IN2009/000301
Publication Date:
April 14, 2011
Filing Date:
May 26, 2009
Export Citation:
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Assignee:
ALKEM LAB LTD (IN)
JITENDRA KOUNDINYA (IN)
RAJIV KUMAR (IN)
ASHOK RAMPAL (IN)
DHARMESH KUMAR ARVINDBHAI PATEL (IN)
International Classes:
C07D209/88
Domestic Patent References:
WO2008084494A12008-07-17
WO2007144900A22007-12-21
WO2008002683A22008-01-03
Foreign References:
US4503067A1985-03-05
Attorney, Agent or Firm:
KHER SANJAY (Clover House176-A, Vaishali, Sir Bhalchandra Road,Hindu Colony, Dadar, Mumbai 4, IN)
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