Title:
PRODUCTION METHOD FOR COMPOSITION FOR FORMULATION AND PRODUCTION METHOD FOR FORMULATION
Document Type and Number:
WIPO Patent Application WO/2023/145869
Kind Code:
A1
Abstract:
Provided are a method for producing a composition for a formulation and a method for producing a formulation that prevent degradation of a drug during production and can readily provide a formulation with excellent granulation properties and high hardness. This method for producing a composition for a formulation comprises step 1 for kneading and granulating a mixture containing an active component and a binder in a barrel by twin-screw extrusion, wherein the temperature in the barrel is 130°C or lower, the binder has a mass average molecular weight of 1,000,000 g/mol or less and the mixture contains 80% by mass or more active component relative to the total mass of the active component and the binder.
More Like This:
Inventors:
FUJISAKI MOTOHARU (JP)
KIMURA AKIRA (JP)
KIMURA AKIRA (JP)
Application Number:
PCT/JP2023/002611
Publication Date:
August 03, 2023
Filing Date:
January 27, 2023
Export Citation:
Assignee:
SUMITOMO SEIKA CHEMICALS (JP)
International Classes:
A61K9/20; A61K31/167; A61K45/00; A61K47/32; A61K47/34; A61K47/38
Domestic Patent References:
| WO2007072908A1 | 2007-06-28 |
Foreign References:
| JP2016511223A | 2016-04-14 | |||
| JP2015500273A | 2015-01-05 | |||
| JP2004524300A | 2004-08-12 | |||
| JP2008540540A | 2008-11-20 | |||
| JP2018507180A | 2018-03-15 |
Attorney, Agent or Firm:
SAEGUSA & PARTNERS (JP)
Download PDF: