Title:
RESTLESS LEGS SYNDROME/PERIODIC APPENDICULAR DYSKINESIA MODEL ANIMAL
Document Type and Number:
WIPO Patent Application WO/2005/115134
Kind Code:
A1
Abstract:
A model animal for restless legs syndrome/periodic appendicular dyskinesia. As a result of administration to the abdominal cavity of mouse of a plasma component of peripheral blood collected from renal failure patients judged as suffering restless legs syndrome/periodic appendicular dyskinesia, it has been found that the mouse strikingly exhibits behavior peculiar to these diseases and hence can be used as a disease model mouse. This model animal can be used in identifying of the causative agent of restless legs syndrome/periodic appendicular dyskinesia and in development and evaluation of any methods of diagnosis and treatment for these diseases.
More Like This:
Inventors:
KADOTANI HIROSHI (JP)
Application Number:
PCT/JP2005/009517
Publication Date:
December 08, 2005
Filing Date:
May 25, 2005
Export Citation:
Assignee:
JAPAN SCIENCE & TECH AGENCY (JP)
KADOTANI HIROSHI (JP)
KADOTANI HIROSHI (JP)
International Classes:
A01K67/027; A61K49/00; (IPC1-7): A01K67/027
Foreign References:
| JP2002544474A | 2002-12-24 |
Other References:
TAKAKI J. ET AL.: "Clinical and psychological aspects of restless legs syndrome inuremic patients on hemodialysis.", AM.J. KIDNEY DIS., vol. 41, no. 4, 2003, pages 833 - 839, XP002990346
COLLADO-SEIDEL V. ET AL.: "Clinical and biochemical findings in uremic patients with and without restless legs syndrome.", AM.J.KIDNEY DIS., vol. 31, no. 2, 1998, pages 324 - 328, XP002990347
See also references of EP 1757186A4
COLLADO-SEIDEL V. ET AL.: "Clinical and biochemical findings in uremic patients with and without restless legs syndrome.", AM.J.KIDNEY DIS., vol. 31, no. 2, 1998, pages 324 - 328, XP002990347
See also references of EP 1757186A4
Attorney, Agent or Firm:
Tsuburaya, Toru (Osaka Ekimae Dai-3 Bldg., 1-1-3, Umeda,,
Kita-ku, Osaka-sh, Osaka, JP)
Download PDF: