Title:
SULFONAMIDE-ARYL AMIDE COMPOUND AND USE THEREOF AS DRUG FOR TREATING HEPATITIS B
Document Type and Number:
WIPO Patent Application WO/2018/121689
Kind Code:
A1
Abstract:
The present invention provides a sulfonamide-aryl amide compound and a use thereof as a drug for treating hepatitis B. Particularly, the present invention provides a compound as an HBV replication inhibitor and having the structure shown in chemical formula (A), a stereoisomer, cis-trans isomer, or tautomer thereof, or a pharmaceutically acceptable salt, hydrate, or solvate thereof. The definition of each group can be found in the specification. The present invention also provides a pharmaceutical composition comprising said compound, and a use thereof in treating hepatitis B.
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Inventors:
WANG ZHE (CN)
WANG XIAOGUANG (CN)
LU CENBIN (CN)
FAN GUOQIN (CN)
WANG XIAOGUANG (CN)
LU CENBIN (CN)
FAN GUOQIN (CN)
Application Number:
PCT/CN2017/119531
Publication Date:
July 05, 2018
Filing Date:
December 28, 2017
Export Citation:
Assignee:
SHANGHAI LONGWOOD BIOPHARMACEUTICALS CO LTD (CN)
International Classes:
C07D207/34; A61K31/40; A61K31/415; A61P1/16; A61P29/00; A61P31/20; A61P35/00; C07D231/16; C07D231/40
Domestic Patent References:
| WO2016183266A1 | 2016-11-17 | |||
| WO2017156255A1 | 2017-09-14 | |||
| WO2004052852A1 | 2004-06-24 |
Foreign References:
| CN105431413A | 2016-03-23 |
Attorney, Agent or Firm:
XU & PARTNERS, LLC. (CN)
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