Title:
TGF-β INHIBITOR COMPOUND AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/032589
Kind Code:
A1
Abstract:
Provided are a TGF-β inhibitor compound and use thereof. In particular, provided is a compound represented by formula (I) or formula (II) or an isotopically labeled compound, an optical isomer, a geometric isomer, a tautomer, an isomer mixture, a pharmaceutically acceptable salt, a prodrug, or a metabolite thereof. Further provided is use of the compound in medicine.
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Inventors:
LU LIANG (CN)
LIU XIAO (CN)
ZHAO SAISAI (CN)
ZHANG LONGZHENG (CN)
HUANG HAI (CN)
ZHANG JIXUAN (CN)
ZHU JUNJIE (CN)
WANG XIAOLONG (CN)
CHEN JIAXIN (CN)
LING SHANCUN (CN)
LIAO XINWEI (CN)
LIU XIAO (CN)
ZHAO SAISAI (CN)
ZHANG LONGZHENG (CN)
HUANG HAI (CN)
ZHANG JIXUAN (CN)
ZHU JUNJIE (CN)
WANG XIAOLONG (CN)
CHEN JIAXIN (CN)
LING SHANCUN (CN)
LIAO XINWEI (CN)
Application Number:
PCT/CN2023/111688
Publication Date:
February 15, 2024
Filing Date:
August 08, 2023
Export Citation:
Assignee:
HENAN MEDINNO PHARMACEUTICAL TECH CO LTD (CN)
International Classes:
A61K31/4439; C07D487/04; A61K31/444; A61P3/00; A61P9/00; A61P13/12; A61P17/00; A61P19/02; A61P19/10; A61P31/12; A61P35/00; C07D519/00
Domestic Patent References:
| WO2007076127A2 | 2007-07-05 | |||
| WO2007076086A2 | 2007-07-05 | |||
| WO2018068759A1 | 2018-04-19 |
Foreign References:
| CN107207531A | 2017-09-26 |
Attorney, Agent or Firm:
BEIJING EAST IP LTD. (CN)
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