Title:
TYROSINE KINASE 2 (TYK2) DEGRADATION COMPOUNDS AND METHODS OF USE
Document Type and Number:
WIPO Patent Application WO/2022/100710
Kind Code:
A1
Abstract:
This disclosure relates to heterobifunctional compounds (e.g., bi-functional small molecule compounds), compositions comprising one or more of the heterobifunctional compounds, and to methods of use the heterobifunctional compounds for the treatment of certain disease in a subject in need thereof. The disclosure also relates to methods for identifying such heterobifunctional compounds.
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Inventors:
LIU JING (US)
CHEN LIQUN (CN)
WANG JIALIANG (US)
HAN XIAORAN (CN)
WU ZHAOHUI (US)
YANG TING (CN)
ZHANG CHENGWEI (CN)
CHEN LIQUN (CN)
WANG JIALIANG (US)
HAN XIAORAN (CN)
WU ZHAOHUI (US)
YANG TING (CN)
ZHANG CHENGWEI (CN)
Application Number:
PCT/CN2021/130434
Publication Date:
May 19, 2022
Filing Date:
November 12, 2021
Export Citation:
Assignee:
CULLGEN SHANGHAI INC (CN)
International Classes:
C07D401/14; A61K31/501; A61P35/00; A61P37/00; C07D417/14
Domestic Patent References:
| WO2020200291A1 | 2020-10-08 | |||
| WO2020069117A1 | 2020-04-02 |
Foreign References:
| CN104884454A | 2015-09-02 |
Attorney, Agent or Firm:
XU&PARTNERS, LLC. (CN)
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