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Title:
UBIQUITIN-SPECIFIC PROTEASE
Document Type and Number:
WIPO Patent Application WO2005014804
Kind Code:
A3
Abstract:
The present invention provides novel members of the family of deubiquitinating enzymes (DUBs) as well as biologically, diagnostically or therapeutically useful fragments, derivatives, and homologues thereof, which are useful in research, biological, clinical, therapeutic as well as prognostic and diagnostic purposes. Furthermore, the polynucleotides and polypeptides provided by the present invention are useful for the treatment and diagnosis of breast cancer, leukemia or brain disorders.

Inventors:
BRUENGGER ADRIAN (CH)
CAI RICHARD LIE (US)
KOSSIDA SOPHIA (CH)
PIERRAT BENOIT (FR)
NIRMALA NANGUNERI R (US)
Application Number:
PCT/EP2004/008798
Publication Date:
June 30, 2005
Filing Date:
August 05, 2004
Export Citation:
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Assignee:
NOVARTIS AG (CH)
NOVARTIS PHARMA GMBH (AT)
BRUENGGER ADRIAN (CH)
CAI RICHARD LIE (US)
KOSSIDA SOPHIA (CH)
PIERRAT BENOIT (FR)
NIRMALA NANGUNERI R (US)
International Classes:
C12N9/64; (IPC1-7): C12N15/12; C12N9/64
Domestic Patent References:
WO2002000860A22002-01-03
Other References:
DATABASE WPI Section Ch Week 200344, Derwent World Patents Index; Class B04, AN 2003-460661, XP002314214
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