Title:
USE OF WEE1 KINASE INHIBITORS IN THE TREATMENT OF CANCER
Document Type and Number:
WIPO Patent Application WO/2023/093840
Kind Code:
A1
Abstract:
This disclosure relates to the use of Wee1 kinase inhibitors in the treatment of cancer. In particular, the disclosure provides the use of Wee1 kinase inhibitors in the preparation of drugs for the treatment of cancers with FBXW7 or CHD4 mutation.
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Inventors:
HSIEH CHIH YI (CN)
TIAN YE EDWARD (CN)
CAI SUI XIONG (CN)
ZHANG CONG CONG (CN)
GUO MING CHUAN (CN)
ZHAO YU XIAO (CN)
XIA HUAN (CN)
TIAN YE EDWARD (CN)
CAI SUI XIONG (CN)
ZHANG CONG CONG (CN)
GUO MING CHUAN (CN)
ZHAO YU XIAO (CN)
XIA HUAN (CN)
Application Number:
PCT/CN2022/134300
Publication Date:
June 01, 2023
Filing Date:
November 25, 2022
Export Citation:
Assignee:
IMPACT THERAPEUTICS SHANGHAI INC (CN)
International Classes:
A61K31/5377; A61K31/519; A61K45/06; A61P35/00; A61P35/02
Domestic Patent References:
| WO2018090939A1 | 2018-05-24 | |||
| WO2019011228A1 | 2019-01-17 | |||
| WO2021073491A1 | 2021-04-22 |
Other References:
YANG YANGYANG, SHUJING LI, HUIJIAN WU: "The Function of F-box Protein Family in Tumorigenesis", CHINESE JOURNAL OF CELL BIOLOGY, vol. 37, no. 8, 31 July 2015 (2015-07-31), pages 1180 - 1186, XP093068702, DOI: 10.11844/cjcb.2015.08.0122
CAO LI-NA, YIN XIANG-HUA: "Research Status of the Expression of CHD4,FBXW7 and SPOP Gene in Endometrial Cancer", MEDICAL RECAPITULATE, vol. 20, no. 1, 1 January 2014 (2014-01-01), pages 44 - 45, XP093068704, DOI: 10.3969/j.issn1006-2084.2014.01.016
CAO LI-NA, YIN XIANG-HUA: "Research Status of the Expression of CHD4,FBXW7 and SPOP Gene in Endometrial Cancer", MEDICAL RECAPITULATE, vol. 20, no. 1, 1 January 2014 (2014-01-01), pages 44 - 45, XP093068704, DOI: 10.3969/j.issn1006-2084.2014.01.016
Attorney, Agent or Firm:
SHANGHAI PATENT & TRADEMARK LAW OFFICE, LLC (CN)
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