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WO/1997/017104A1 |
A flexible source wire (10) is provided containing a radioactive source (160) that is capable of maneuvering through a tortuous narrow passage to a treatment site within the body. This source wire (10) includes an elongated flexible hous...
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WO/1997/016221A2 |
The present invention provides a method to achieve radioisotopic localization at tumor sites, i.e., a method of enhancing radiolabeled ligand localization to a tumor in an individual in need of such treatment, comprising the steps of: tr...
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WO/1997/014445A1 |
This invention presents a series of novel tropane-based derivatives complexed with either technetium or rhenium that are specific for central nervous system receptors, in particular, dopamine or serotonin receptors. The compounds of the ...
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WO/1997/003722A1 |
An irradiation apparatus has at least one exchangeable radiation source that may be moved by means of a transport cable between at least one rest position and at least one irradiation position and a long-distance transport container for ...
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WO/1996/040289A1 |
A method of radiolabeling a peptide, e.g., somatostatin or an analogue thereof or vasoactive intestinal peptide, with a radioisotope of technetium or rhenium, comprises the steps of: (a) reacting the peptide with an acetyl-protected t-th...
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WO/1996/040352A1 |
A flexible source wire (10) is provided containing a radioactive source (160) that is capable of maneuvering through a tortuous narrow passage to a treatment site within the body. This source wire (10) includes a thin flexible housing tu...
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WO/1996/035477A1 |
An after loader for use in radiation oncology or intravascular radiotherapy comprises a wire storage mechanism (10) for storing a radioactive tipped source wire (62), a drive mechanism (20) for advancing the source wire (62) into a cathe...
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WO/1996/034656A1 |
An apparatus has a radioactive source projector connected to a source locator (10) by a plurality of radioactive source transfer tubes (15). The locator has two sides (11, 12), the first of which comprises connecting means (13) for conne...
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WO/1996/032968A1 |
The present invention relates to a class of compounds having affinity for certain cancer cells, e.g. lung carcinomas, colon carcinomas, renal carcinomas, prostate carcinomas, breast carcinomas, malignant melanomas, gliomas, neuroblastoma...
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WO/1996/031243A1 |
This invention provides novel radiopharmaceuticals which are useful as imaging agents for the diagnosis of cardiovascular disorders, infectious diseases and cancer. The radiopharmaceuticals are comprised of phosphine or arsine ligated te...
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WO/1996/022121A1 |
A balloon catheter (1) has at least one radionuclide species in or on the wall of the balloon (2) in order to remedy vessel restrictions or stenoses and to prevent restenosis in arteries (6), veins or vessel implants or reduce the growth...
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WO/1996/020735A2 |
Nanoparticulate crystalline x-ray contrast agents are formulated with stabilizers to enhance contact between the crystalline x-ray contrast agents and the gastrointestinal tract. Nanoparticulate crystalline therapeutic substances also fo...
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WO/1996/017654A1 |
Apparatus and methods are provided for delivering an easily controllable inherently uniform dosage of radiation to the walls of a blood vessel for preventing restenosis after angioplasty. The apparatus comprises a catheter (10) having a ...
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WO/1996/015830A1 |
Safe, isotopically pure Pd-103-containing seeds (10) of high apparent activity are formed by bombarding an Rh target in a cyclotron with high energy particles to obtain Rh containing carrier-free Pd-103, separating therefrom the carrier-...
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WO/1996/014898A1 |
This invention is a method and apparatus for intravascular radiotherapy for prevention of stenosis following angioplasty or other trauma to coronary arteries (30) caused by smooth muscle cell hyperplasia in which a uniform dosage of radi...
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WO/1996/013303A1 |
This invention is an apparatus and method for delivering a treating element (22), such as a radiation source, through a catheter (60) to a desired site in a vascular system of a patient, such as a coronary artery, for inhibiting the form...
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WO/1996/010436A1 |
An apparatus for treating an occlusion or constriction, such as a stenosis (30) in a blood vessel (26) or other conduit in the body, as well as an apparatus for treating bodily disease (e.g., a tumor or cancerous area) occurring around a...
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WO/1996/006654A1 |
This invention is a catheter (10) for use with a radioactive source (16) within the catheter (10) to irradiate a selected area of a blood vessel in combination with angioplasty procedures, to prevent restenosis of that area of the blood ...
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WO/1995/034346A1 |
An ablation and mapping catheter is disclosed which incorporates a fluid electrode for contacting tissue. The fluid emerges along the length of the catheter to generate a linear lesion in the cardiac tissue.
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WO/1995/033511A1 |
The present invention is an implantable device that is capable of delivering a therapeutic agent to a tissue or organ over a long period of time. The implantable device is especially suited for treating tissues and organs that are compri...
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WO/1995/033512A1 |
A flexible source wire (10) is provided containing a radioactive source (16) that is capable of maneuvering through a tortuous narrow passage to a treatment site within the body. The source wire (10) includes a thin flexible housing tube...
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WO/1995/026681A1 |
This invention is an apparatus and method for treating an occlusion or constriction, such as a stenosis (30) in a blood vessel (26) or other conduit in the body, as well as an apparatus and method for treating a tumor or cancerous area o...
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WO/1995/019807A1 |
This invention is an apparatus guided by a guide wire (9) within a patient's artery for reducing restenosis after arterial intervention in the patient's artery. A radiation dose delivery wire (8) with a radiation source (8d, 8e, 8f) enca...
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WO/1995/016489A1 |
The radiation-therapy device proposed has a flexible mat (1) which is placed over the part of the patient's body to be treated. Running in the plane of the mat (1) are prefabricated channels (7) designed to accommodate tubular inserts (2...
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WO/1995/010314A1 |
The invention relates to an implant injection device for once-only use, said device comprising an elongated implant container or housing (10), a cannula (11) and a plunger (20) which is displaced longitudinally within the implant housing...
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WO/1995/007732A1 |
A radiotherapy device comprises a radioactive wire adapted to deliver an intended dosage of radiation to a lesion or other selected body tissues. The radioactive wire comprises an inner core about which is disposed an outer buffer layer ...
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WO/1995/002429A1 |
This invention is an over-the-wire rapid exchange catheter (10) having a two part guide wire channel or a full length guide wire channel. The full length guide wire channel has a rupturable membrane (60) along one side. The catheter is e...
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WO/1994/026205A1 |
A vascular implant for preventing and/or eliminating vasoconstrictions contains at least one species of radionuclides whose half-life value lies between 7 hours and 100 days. As long as restenosis is to be feared, the tissues adjacent to...
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WO/1994/025106A1 |
A source wire (38) having a radioactive source (40) at its distal tip (45) is used to treat tissue at a target site within a patient's body by localized in vivo radiation. The source wire (38) is advanced to the target site along a pathw...
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WO/1994/023789A1 |
A device for introduction of a source of radioactive radiation (14) into a body. The device having a flexible cable (10) which can be introduced into the body and a titanium capsule (12) for sealingly containing a radioactive source (14)...
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WO/1994/003191A1 |
This invention provides an immunoconjugate which comprises 1) a non-peptidyl toxin and 2) a CD4-gamma2 chimeric heavy chain homodimer linked thereto. This invention also provides an immunoconjugate which comprises 1) a gamma radiation-em...
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WO/1993/023110A1 |
The present invention relates to a method and a device for injecting humans and animals with a pharmaceutical preparation, wherein the preparation is held in a rigid carrier (5) and the carrier is carried through the skin into the body b...
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WO/1993/014774A1 |
Aqueous solutions containing peroxobisulphate ions are used to prepare medicaments for treating malignant cells in the human and animal body. Also disclosed are a process and device for preparing these therapeutical agents, which may be ...
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WO/1993/004735A1 |
Method and apparatus (10) for treatment and post-treatment of the stenosed region (14) of an artery (12) after reduction of the region by angioplasty or other means by applying a radioactive dose (30) to said reduced region of the artery...
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WO/1992/022350A1 |
A completely implantable apparatus (26) is provided for treatment of tissue surrounding a cavity (24) left by surgical removal of a brain tumor (18). The apparatus (26) includes an inflatable balloon (28) constructed for placement in the...
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WO/1992/012744A1 |
An implanting gun apparatus (10) is described. A drive rod (23) is linearly moveable in a handle assembly (11) by a first pivotable linkage (16) actuated by a trigger (14), to urge a pellet (101) from a carrier (100) through a head assem...
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WO/1992/010932A1 |
A microwave radiator (11) formed of a radioactive substance and adapted to simultaneously deliver microwave energy and nuclear radiation to living tissue (32). The radiator (11) is incorporated into an interstitial or intracavitary probe...
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WO/1992/000776A1 |
The invention relates to a device for introducing a source of radioactive radiation into the body for therapeutic applications, comprising a flexible cable (10) to be introduced into the body through a catheter and a capsule (12), for se...
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WO/1991/012048A1 |
A device for implanting an object, such as a hormone pellet or an electronic transponder beneath the skin of an animal, comprises a hollow needle (1) with an actuating rod (11) slidable therein, a cover (2) movable relative to the needle...
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WO/1990/003827A1 |
Apparatus (10) for in situ radiotherapy has a flexible catheter (12) having a proximal end (22) for receiving a radioisotope and a distal end (20) for positioning the flexible catheter (12) within a patient to be treated. An anchor (14),...
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WO/1990/003200A2 |
The invention relates to a device for the oral administration of a radioactive liquid, comprising: a reservoir for the radioactive liquid to be enclosed within a shielding sleeve, a separate holder for rinsing liquid to be accommodated o...
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WO/1989/012631A1 |
A group of functionalized polyaminocarboxylate chelants that form complexes with rare earth-type metal ions are disclosed. The complexes can be covalently attached to an antibody or antibody fragment and used for therapeutic and/or diagn...
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WO/1988/008318A1 |
A plaster containing active ingredients for controlled administration of active ingredients to the skin and possessing a rear side and a skin side, has a rear layer, an active ingredient reservoir containing one or more active ingredient...
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WO/1986/004248A1 |
Particles or "seeds" (10) are manufactured for implantation into tumours within a human body for emitting X-rays to destroy or reduce the tumours. The seeds contain palladium (14) which is substantially enriched in a palladium-102 and wh...
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WO/1985/002779A1 |
A catheter (20) for use in treating tumors is flexible and relatively small in diameter so that it can be inserted interstitially into the tumor mass (T). A conductor (24) is provided along the length of the catheter (20) and is electric...
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JP2024052342A |
An object of the present invention is to provide a phototherapy device in which a reflector is less likely to be damaged when a balloon is expanded. The present invention includes a balloon that forms an internal space in which a light e...
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JP2024052339A |
An object of the present invention is to provide a phototherapy device that can irradiate light to the vicinity of the cervix and at the same time irradiate light to the vaginal wall in a limited manner in the circumferential direction, ...
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JP7460623B2 |
An apparatus and methods for embolization of a patient includes vials for containing radiomicrospheres including inclined and domed base are described. Apparatus for delivering the microspheres from the vials to a patient for radioemboli...
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JP7451554B2 |
Embodiments of the disclosure may be drawn to brachytherapy applicators. Exemplary applicators may include an interstitial tube having a body with a proximal end and a distal end and a central conduit extending from the distal end of the...
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JP2024511074A |
Custom radioactive seed carriers are created preoperatively and/or intraoperatively to more closely match the carrier specifications of a radiation treatment plan for a particular patient. One or more carrier-specific components, such as...
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