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WO/2023/152050A1 |
The invention relates to a control method comprising: - between a time tdi and a time tmi: - controlling (112) a first actuator so as to move a first piston of the syringe into a liquid reservoir; and - controlling (112) a second actuato...
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WO/2023/154554A1 |
The present disclosure relates to materials and methods for large-scale spatial transcriptomics. In particular, the disclosure provides methods for producing systems for spatial transcriptomics, along with materials and methods for deter...
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WO/2023/150829A1 |
A vented piston is receivable within a fluid conduit. The piston comprises a plunger body, the plunger body defining a fluid flow path extending between an upstream end and a downstream end; a fluid check-valve disposed across the fluid ...
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WO/2023/152519A2 |
Provided herein are methods of cell-free protein synthesis, optimised cell-free protein synthesis (CFPS) reagents and the post translational modification of the expressed proteins, to increase protein expression yields. The methods are a...
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WO/2023/154280A1 |
A biological sample collection system and dispensing system is described. The biological sample collection system provides for collection and processing of a biological sample (i.e. bodily fluids collected from nose, throat, or other muc...
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WO/2023/151243A1 |
The present application provides a lyosphere pre-embedding structure, a digital microfluidic chip, and a pre-embedding and liquid injection method. The lyosphere pre-embedding structure comprises a freeze-dried blister and a sample injec...
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WO/2023/151567A1 |
The present invention relates to a sinuous microstructure mixing unit, and also relates to a microfluidic device having the unit, and the use of the unit or the device for preparing nanoparticles, such as lipid nanoparticles or self-asse...
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WO/2023/154110A1 |
Disclosed herein is an apparatus for processing fluid samples such as blood or blood products. Also disclosed are devices comprising the apparatus as well as methods for separating plasma from blood or blood products using said apparatus.
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WO/2023/148489A1 |
The present invention relates to devices and methods for collecting and manipulating liquid samples.
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WO/2023/147977A1 |
The invention relates to a microfluidic device (1) comprising capillary traps (5) each provided with a microcavity (6) formed on a wall of a microchannel (2) for circulating a fluid and with a retaining member (7) extending in the microc...
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WO/2023/150310A1 |
A chip module configured for use with a fluid sample processing system can include one or more assay devices arranged into one or more rows. The assay device(s) can include one or more wells configured to hold fluid therein and one or mo...
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WO/2023/147674A1 |
Provided herein are reagent plates, digital microfluidics ("DMF") cartridges and systems, and methods for using the same. The reagent plate may be used for easily preparing, storing, stabilizing, transporting, and/or dispensing reagents ...
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WO/2023/150232A1 |
A system and/or method for determining an immune activation state of a subject can include: deforming leukocytes within a microfluidic channel, acquiring a plurality of images of the leukocytes, determining biophysical parameters of the ...
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WO/2023/147908A1 |
In a device (1) and a method for examining and processing a biological or medical sample, a dispensing unit (3) serves to dispense the sample into a depression of a sample holder (10). The sample holder (10) has an aspect ratio of the he...
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WO/2022/245826A9 |
The present invention includes compositions and methods for using and manufacturing hydrogel template particles with micropores and/or a nanoporous structure.
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WO/2023/150378A1 |
An automated sampling platform includes a gantry-style 2D or 3D actuator equipped with a syringe pump end effector configured to extract samples from a rubber septum placed in-line within a tubing-based system and to deposit the extracte...
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WO/2023/149787A1 |
The present invention relates to a nucleic acid analysis device including an infectious agent separation and concentration function. The present invention provides a nucleic acid analysis device including an infectious agent separation a...
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WO/2023/141944A1 |
A separation apparatus (100), comprising a separation chip (10, 10'), an oscillation system (70), a differential pressure driving system (50), a frequency conversion module (40) and a controller (60). The separation chip (10, 10') compri...
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WO/2023/146022A1 |
A liquid refining apparatus is disclosed. The liquid refining apparatus includes a substrate, a loader which is formed on the substrate and configured to receive a first liquid, a filter which is configured to reduce a concentration of a...
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WO/2023/144553A1 |
A microfluidic network of a polymeric microfluidic strip includes a liquid sample input port, a reagent zone, a detection zone, and a compressible chamber in fluidic communication via the microfluidic network. A polymer layer overlies th...
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WO/2023/144192A1 |
The invention relates to a device which is preferably microfabricated, having a positioning device for sequential positioning of particles, wherein the positioning device has a preferably rigid delimitation structure, wherein the delimit...
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WO/2023/142260A1 |
An on-chip microgroove array digital PCR chip based on electrical impedance detection, comprising a microgroove array, a power supply module, a clock generation module, a digital control logic module, a driving module, an analog-to-digit...
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WO/2023/143004A1 |
A liquid injection apparatus, a detection method, and a medical device. The liquid injection apparatus comprises a mounting bracket (10), a diluent container (20), and a liquid injection assembly (30). The mounting bracket (10) is provid...
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WO/2023/144713A1 |
Apparatus and methods are described for analyzing a bodily sample. A sample carrier (22), which houses the bodily sample, includes at least one fluidic channel (120), at least one analysis chamber (68), and a receptacle (92) that houses ...
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WO/2023/146869A1 |
Devices, systems, and methods related to autonomous directional valves that allow fluids to stop and flow based on progressive changes in pressure are generally described.
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WO/2023/147003A1 |
The present subject matter relates to devices and techniques for reducing the parabolic velocity profile. The disclosed device can include a coflow generator configured to receive a buffer solution and a mixture of at least two component...
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WO/2023/146021A1 |
A fluid separation apparatus is disclosed. The fluid separation apparatus includes a diluter which includes a first filter channel through which a fluid flows, a fluid structure formed to protrude outward from the first filter channel an...
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WO/2023/147002A1 |
Various embodiments described herein include methods and devices for the evaluation of sub-cellular and molecular structures of cells and particles. In one aspect, a microfluidic device includes: (i) a sensor positioned adjacent to a mic...
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WO/2023/147356A1 |
A cell deactivation device includes a cell deactivation container. The cell deactivation container includes a plurality of microfluidic channels, a lid covering the plurality of microfluidic channels, the lid having a thickness of less t...
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WO/2023/146067A1 |
The present invention provides a biofluid sample preprocessing apparatus and a biofluid sample preprocessing method using same, the biofluid sample preprocessing apparatus comprising: a sample inlet; a medium inlet; a central fluid chann...
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WO/2023/146594A1 |
A gastrointestinal simulator system includes a thermoregulated bath, two glass beakers situated within the thermoregulated water bath, and a pump. The beakers simulate the stomach and intestines and are coupled together using a tube. A s...
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WO/2023/147000A1 |
A microfluidic device and a method for sensing and sorting of cells or particles in a microfluidic channel are disclosed. The microfluidic device may include a substrate with a microfluidic channel having an inlet, the microfluidic chann...
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WO/2023/146456A1 |
A material mixing cartridge for a dispensing system comprises a dispensing chamber, with a material dispensing outlet and a dispensing actuator for dispensing material through the material dispensing outlet. The mixing cartridge further ...
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WO/2023/146404A1 |
A device for detecting at least one analyte, for example a cell, in a sample fluid, the device comprising a fluid channel having a longitudinal channel axis and structured to allow the sample fluid containing at least one analyte to pass...
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WO/2023/146870A1 |
Systems and methods related to microfluidic devices (e.g., microfluidic devices comprising layers of films) are generally described. In some embodiments, a microfluidic device comprises a substrate configured to facilitate fluid transpor...
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WO/2023/144530A1 |
The described invention is a cell counting device for counting target cells within a fluid, the device comprising: a microfluidic channel configured to receive a flow of a cell-containing fluid through an inlet and conduct the flow of th...
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WO/2023/026286A9 |
Methods and apparatus are disclosed for preparing plasma enriched with Interleukin Receptor 1 antagonist ("IL-IRa") using glass beads or polyacrylamide microbeads and recovering the plasma enriched in IL-IRa with a filter.
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WO/2023/141047A1 |
An assembly for securing a film to an object is provided. The assembly may comprise a lid comprising a surface configured to receive the film, where the surface comprises a plurality of vent openings through which positive pressure or va...
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WO/2023/141284A1 |
A microfluidic valve comprising an adhesive tape, an outlet disposed at one end of a first microfluidic channel, an inlet disposed at one end of a second microfluidic channel, wherein the inlet and the outlet are disposed in a proximity ...
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WO/2023/138655A1 |
It relates to methods, reagents, compositions, and systems for particle distribution and cell analysis. Cells and adjustable droplets each with a particle encapsulated therein can be distributed into microwells of a microwell array. The ...
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WO/2023/138858A1 |
The invention relates to a method for marking objects made of plastic for laboratory use, wherein a dark-colored contrast surface is produced in the plastic of the object using laser beams, and a light-colored writing is produced in the ...
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WO/2023/141244A1 |
A microfluidic device for droplet electroporation includes a channel having an inlet, and outlet, a channel thickness, a channel width, and a first end and a second end defining a channel length, wherein the channel is configured to rece...
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WO/2023/138793A1 |
Device (1) for receiving biological samples for carrying out a PCR analysis method for determination of pathogenic microorganisms, in particular pathogenic viruses, especially viruses that cause respiratory diseases, having - a receiving...
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WO/2023/141476A1 |
Disclosed are assemblies, systems, and methods for transilluminating a sample disposed within a device. An assembly includes a first optically transparent substrate configured to receive a biological sample, a second optically transparen...
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WO/2023/138988A1 |
The invention relates to a method for separating HMW DNA and/or UHMW DNA from a carrier element (8), to which the DNA is removeably attached, using a centrifugation container set (2) with at least one centrifugation container (10a, 10b, ...
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WO/2023/139272A1 |
The present invention relates to a device for creating a cylindrical hydrogel.
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WO/2023/139383A1 |
The present invention concerns a connector including a housing, extending between a distal end and a proximal end; a hollow needle mounted, at least partially, within the housing, a first end of the hollow needle being connected or conne...
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WO/2023/140613A1 |
The present invention provides a fluorometric assay substrate for the simultaneous measurement of glucose and lactate, wherein an identical substrate (Amplex Red) that reacts with glucose and lactate and a catalyst (horseradish peroxidas...
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WO/2023/137645A1 |
The methods, reagents, compositions, and systems for particle distribution and cell analysis. Cells and adjustable droplets each with a particle encapsulated therein can be distributed into microwells of a microwell array. The encapsulat...
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WO/2023/138810A1 |
The invention relates to a microfluidic device (100) for processing a sample, wherein the device (100) comprises an amplification functional module (110) having a microfluidic channel (115) for guiding a fluid, a dry reagent pre-storage ...
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