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Matches 1 - 50 out of 1,436

Document Document Title
WO/2022/165382A1
The invention provides compositions and methods for the treatment of anxiety, panic disorder, seasonal affective disorder (SAD), and other psychological disorders. In particular, the invention provides combination treatment methods invol...  
WO/2022/121317A1
Disclosed is a 1,1'-biphenyl-2,6-diphenolic compound and the use thereof. The 1,1'-biphenyl-2,6-diphenolic compound is a new compound, and has good biological activity. By means of in vitro tumor cell activity experiments, it was found t...  
WO/2022/107139A1
The present invention is directed to a process for the preparation of a hydrazine derivative by reaction of the corresponding oxirane with hydrazine, that uses as only solvent toluene. The process provides excellent yields and purities a...  
WO/2022/043374A1
The present invention relates to compounds of formula (II) wherein R1-R5, X and L are as described herein, and pharmaceutically acceptable salts thereof, compositions including the compounds and methods of using the compounds, particular...  
WO/2021/252640A1
The present disclosure relates to compounds of formulas (A) and (I), pharmaceutically acceptable salts thereof, and solvates of any of the foregoing, pharmaceutical compositions comprising the same, methods of preparing the same, interme...  
WO/2021/246479A1
One purpose of the present invention is to provide a novel dihydrazide compound. Another purpose of the present invention is to provide: a curable resin composition which contains the above-described dihydrazide compound and exhibits exc...  
WO/2021/200694A1
[Problem] To provide a novel compound that has read-through activity and is useful as an agent for preventing or treating nonsense-mutation genetic disorders. [Solution] One embodiment of the present invention provides a compound represe...  
WO/2021/187748A1
According to an aspect, a method for selectively modifying nucleotides comprises a step for reacting nucleotides and a compound of formula 1 in the presence of a rhodium catalyst, wherein the O6 position of a guanine among the four bases...  
WO/2021/152564A1
Disclosed is a method for purifying a crude adiponitrile stream by differential volatility comprising separating at least a portion of the components of the crude adiponitrile stream by flashing vapor from a liquid film.  
WO/2021/125307A1
The present invention addresses the problem of providing a novel crystal. A crystal of 3-hydroxy-N'-(1,3-dimethylbutylidene)-2-naphthoic acid hydrazide having a maximum intensity peak at 6.9° as a diffraction angle (2θ) in a powder X-r...  
WO/2021/125306A1
The present invention addresses the problem of providing a novel crystal. A crystal of 3-hydroxy-N'-(1, 3-dimethylbutylidene)-2-naphthoic acid hydrazide which has a peak with the maximum intensity at a diffraction angle (2θ) of 6.1 ± 0...  
WO/2021/119606A1
The disclosure provides, inter alia, safe and environmentally-friendly methods, such as flow chemistry, to synthesize isocyanates, such as methylene diphenyl diisocyanate, toluene diisocyanate, hexamethylene diisocyanate, isophorone diis...  
WO/2021/111022A1
The present invention relates to to sulfated phenylhydrazide derivatives of formula (I) as antiviral agents. Said compounds are therefore useful for the prevention and/or treatment of viral diseases such as the disease caused by Ebola vi...  
WO/2021/089011A1
Provided are a compound with a bishydrazide structure represented by formula I, and a preparation method therefor and the use thereof. The compound with a bishydrazide structure can enhance the activity of intestinal stem cells, promote ...  
WO/2021/079069A1
The present invention relates to novel energetic salts of formula C+A-, wherein: C+ is a cation derived from an amino acid; A- is an energetic nitrogen-containing anion chosen among the anions derived from dinitramide, trinitromethane (N...  
WO/2021/071493A1
The present disclosure describes multi-fluid kits for printing three-dimensional green body objects, three-dimensional printing kits, and methods of three-dimensional printing. In one example, a multi-fluid kit for printing a three-dimen...  
WO/2021/062559A1
This disclosure relates to carmabinoid derivatives of Formula (1) wherein R4 or R7 is a carboxamide group, pharmaceutical compositions comprising these compounds and methods of using the carmabinoid derivatives. These compounds are poten...  
WO/2020/245468A1
The present invention relates to compounds useful as modulators of sirtuins, in particular as activators of SIRT1. Furthermore, the invention refers to the medical use of such compounds, in particular in the prevention and/or treatment o...  
WO/2020/184336A1
Provided is a liquid metal complex having oxygen-absorbing ability and containing: a cobalt acacene complex or a derivative thereof; and an ionic liquid in which an ionic ligand having an amine structure and a counter ion thereof are pai...  
WO/2020/180823A1
Presented herein, in certain aspects, are methods of preventing, reducing, delaying and treating post-operative cognitive dysfunction, or one or more symptoms thereof, by administering a compound disclosed herein to a subject prior to, d...  
WO/2020/180821A1
Presented herein, in certain aspects, are methods of treating or preventing obesity, assisting or inducing weight loss, suppressing appetite, or inhibiting weight gain in a subject by administering a compound of the invention to a subject.  
WO/2020/179671A1
This invention provides: a curable resin composition including a specific polymer precursor, a nonionic compound B, and at least one compound selected from the group consisting of a polymerizable compound and a photosensitive compound, w...  
WO/2020/169682A1
The present invention relates to compounds of the following general formula (I): or a pharmaceutically acceptable salt and/or solvate thereof, their use as a drug, in particular as antibacterial agent, notablyforpreventingand/or treating...  
WO/2020/102936A1
A method for preparing a covalent organic framework (COF) material and a method for reversible condensation polymerization/termination polymerization. The COF material prepared by the present method shows high crystallinity, high specifi...  
WO/2020/094440A1
The invention relates to a process for the synthesis of aryl hydrazinesof formula I or a salt thereof, which process comprises subjecting an arene of formula II to a coupling reaction with hydrazine or a derivative thereof, wherein the c...  
WO/2020/047231A9
Provided are mixtures of dexamethasone- N-methacryloylglycylglycyl hydrazide (MA-Gly-Gly-NHN=Dex) monomers enriched in a desired diastereomer, and polymer compositions of same. Also provided are methods of treating inflammatory condition...  
WO/2020/047668A1
Provided herein are Myc-Max inhibitory compounds having the structure of Formula (I) and compositions thereof for use in the treatment of cancer. In particular, the Myc-Max inhibitory compounds may be useful for the treatment of cancers ...  
WO/2020/051267A1
A self-crosslinking compound and coating compositions including the same as well as compositions capable of forming a ketone or carbonyl-hydrazide crosslink at ambient temperatures that utilizes a modified latent cross linker capable of ...  
WO/2020/040633A1
The present invention generally relates to compounds of Formula (I) disclosed herein, methods for their synthesis and uses thereof. The disclosed compounds may be useful in preventing and/or mitigating microemulsion formation in enhanced...  
WO/2020/026260A1
Present invention discloses novel 2-(3-halo-5-methyl-1H-pyrazol-1-yl)-3-halopyridine compounds and intermediates thereof. Method of preparation of said compounds is also provided. Disclosed compounds are useful as chemical intermediates.  
WO/2020/018779A1
Methods and compositions are provided for treatment of seizure disorders, developmental disorders, neurological disorders, behavioral disorders and addiction with phenylethylidenehydrazine or a pharmaceutically acceptable salt thereof.  
WO/2020/018131A1
An example of a multi-fluid kit for three-dimensional printing includes a binder fluid and an adhesion promoter fluid. The binder fluid includes water and polymer particles in an amount ranging from about 1 wt% to about 40 wt% based on t...  
WO/2020/002338A1
A process for the continuous production of a reaction product of a diazo‐compound and a substrate in a multi‐stage flow reactor is disclosed.  
WO/2019/241851A1
The present invention relates to compounds that have the ability to inhibit lysine biosynthesis via the diaminopimelate pathway in certain organisms. As a result of this activity these compounds can be used in applications where inhibiti...  
WO/2019/232629A1
Chemical-based methods and products for mitigating the impact of an oil spill are disclosed. The products act by herding, thickening, gelling, and reducing adhesiveness. N-fatty acid amino acid (FA-AA) conjugates display oil-herding beha...  
WO/2019/234728A1
The present invention provides THCA- and CBDA-derivatives, and pharmaceutical compositions thereof. These compounds are non-classical cannabinoids that are either agonists or antagonists of the peripheral CB1 and/or CB2 receptors, and ar...  
WO/2019/224138A1
The invention relates to a method for producing compounds of formula (I), (I), based on compounds of formula (II), (II), wherein R1, R2 and R3 have the above meaning and wherein R1 and R3 do not simultaneously represent hydrogen in a com...  
WO/2019/175511A1
The invention relates to a method for producing a bis-hydrazine of formula (I) : (R)(NH2)N-A-N(NH2)(R) (I) in which A and R are as defined in the description, said method comprising: the addition of a compound of formula (III): X-A-X (II...  
WO/2019/175296A1
The present invention relates to a continuous process for the preparation of N-alkyl- nitratoethylnitramines (e.g. NENA compounds, DINA).  
WO/2019/146280A1
A compound which is represented by formula (I). A method for producing this compound according to the present invention comprises a step for reacting a compound represented by formula (II) with one or more compounds represented by formul...  
WO/2019/132739A1
The present invention relates to the field of organic chemistry and pharmacology and describes novel asymmetric derivatives of polyphenols of the dinaphthalene series of general Formula (I) or general Formula (II), a process of preparing...  
WO/2019/115000A1
The present invention relates to a process for the preparation of rucaparib; the invention also refers to novel intermediates of synthesis as well as their use in the preparation of i.a. rucaparib.  
WO/2019/075875A1
Disclosed is an organic amine salt foamer, namely, a composite polyurethane foamer, comprising: 1) hexafluorobutene, and 2) an alkanolamine salt mixture (MAA), the alkanolamine salt mixture (MAA) comprising an organic amine salt compound...  
WO/2019/058885A1
Provided is a method for producing a compound, by which a sulfonate salt of a hydrazine compound is able to be safely produced with high yield. Also provided is a method for producing a compound, by which an acid hydrazide compound deriv...  
WO/2019/025426A1
The invention relates to hydrazide compounds and their use in medicine, particularly in treating and /or preventing infections caused by a fungus.  
WO/2018/183601A1
This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions con...  
WO/2018/150755A1
[Problem] To provide a novel and high-performance nucleating agent for polyolefin resins. [Solution] A compound represented by general formula (1); a nucleating agent comprising the compound; a polyolefin resin composition containing the...  
WO/2018/141069A1
Methods of detecting an aldehyde-containing compound in a subject or in a sample from a subject are described herein, comprising administering an aldehyde-binding compound of Formula I to the subject, or combining such a compound with th...  
WO/2018/145021A1
The invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of Formula I, processes for preparing compou...  
WO/2018/101368A1
The purpose of the present invention is to provide a rubber additive with which it is possible to provide a rubber composition having exceptional low heat build-up properties and workability, a rubber composition including the rubber add...  

Matches 1 - 50 out of 1,436