Login| Sign Up| Help| Contact|

Patent Searching and Data


Matches 851 - 900 out of 1,938

Document Document Title
JPH024215B2  
JPH0222226A
PURPOSE: To obtain the title remedy effective for treating osteopathic disease such as osteoporosis containing a PGD analog compound such as PGD2 or 12-PGJ2 or PGD1 as an active ingredient. CONSTITUTION: A remedy for osteropathic disease...  
JPH02167A
NEW MATERIAL:5-Thia-Δ7-prostaglandin Es expressed by formula I [R1 is H or 1-10C alkyl; R2 is (substituted) 1-10C alkyl or (substituted) cycloalkyl; R3 and R4 are H or protecting group; indication of formula II denotes 7Z, 7E isomer or ...  
JPH0159256B2
NEW MATERIAL:The compound of formula I and formula II (A is O, H or OH; B is -CH=CH- or -C C-; R<1>-R<3> are H or 1-4C alkyl; R<4> is H, OH or protected hydroxyl group; R<5> is 1-10C (substituted) hydrocarbon group; R<6> is H, 1-6C alkyl...  
JPH0159255B2  
JPH0149264B2
A novel prostaglandin analogue of the formula:(wherein the symbol ◄ represents β-configuration, the dotted linie ----- represents a-configuration, and the double bond between (C13-C14 represents transconfiguration) and cyclodextrin cl...  
JPH0149127B2
Stable compositions of PGE-type compounds are achieved by dissolving those compounds in carbonate diester solvents which may contain water up to the solubility limit of the carbonate diester.  
JPH0148266B2  
JPH0148256B2
A process for preparing a 3-oxo-7-hydroxy-bicyclo[3,3,0]octan-2-ylcarboxylic acid ester of the formula wherein R1 is alkyl of 1-6 carbon atoms or phenalkyl of 7-10 carbon atoms and R2 is hydrogen, alkyl or 1-6 carbon atoms, phenalkyl of ...  
JPH0146499B2  
JPH0144699B2  
JPH0144172B2
An E-type prostaglandin in a solvent comprising a mixture of triacetin and ethanol, which has good stability and is rapidly miscible with water.  
JPH01502750A
PCT No. PCT/DE88/00151 Sec. 371 Date Nov. 23, 1988 Sec. 102(e) Date Nov. 23, 1988 PCT Filed Mar. 11, 1988 PCT Pub. No. WO88/07037 PCT Pub. Date Sep. 22, 1988.The invention relates to 6-oxo-prostaglandin E1 derivatives of formula I, (I) i...  
JPH0142938B2
A novel 13-aza-14-oxo-TXA2 analogue of general formula:[wherein symbol A represents(i) a group of general formula: -CH2CH2-(CH2)m-,(ii)) a group of general formula: cis-CH=CH-(CH2)17,(iii) a group of general formula: -CH2O-(CH2)m-,(iv) a...  
JPH0141625B2
The present invention is directed to new 16-methoxy-16-methyl prostaglandin E1 derivatives of the following general formula wherein R stands for a (C1-4) alkyl group or a non-toxic pharmaceutically acceptable cation, to a process for pre...  
JPH0141139B2  
JPH0141147B2  
JPH0141144B2  
JPH0141146B2  
JPH0141145B2  
JPH0141140B2  
JPH0141142B2  
JPH0141143B2  
JPH0140824B2  
JPH0140825B2  
JPH0140813B2  
JPH0140021B2  
JPH0140020B2  
JPH0138104B2  
JPH01502117A
Therapeutical compositions containing products obtained from the addition of thiols to prostaglandines or analogues of prostaglandines. These compositions have an antitumoral activity.  
JPH0129168B2  
JPH01501360A
Process for the manufacture of (-)-oxabicyclo[3.3.0]octanolones of formula (-)-I, where R is hydrogen or the residue (a), in which R1 has the notation of a hydrogen, alkyl with 1-7 C atoms, or phenyl. The process is characterized in that...  
JPH01501281A
PCT No. PCT/DE87/00517 Sec. 371 Date Jul. 13, 1988 Sec. 102(e) Date Jul. 13, 1988 PCT Filed Nov. 12, 1987 PCT Pub. No. WO88/03568 PCT Pub. Date May 19, 1988.A microbiological process for sterospecific monoketo reduction of racemic 3-keto...  
JPH0123445B2  
JPH01110644A
NEW MATERIAL:A compound shown by formula I (R1 is H, alkyl, aralkyl, cycloalkyl, phenyl or 1 equivalent cation; X is O-CH2 or CH2-O; B is trans CH=CH or C≡C; R2 is alkyl, aryloxy, cycloalkyl, alkenyl or phenyl; R1 is H, methyl or vinyl...  
JPH01501229A
PCT No. PCT/DE87/00515 Sec. 371 Date Jul. 13, 1988 Sec. 102(e) Date Jul. 13, 1988 PCT Filed Nov. 12, 1987 PCT Pub. No. WO88/03526 PCT Pub. Date May 19, 1988.The invention relates to a process for manufacturing optically active carbacycli...  
JPH01102059A
NEW MATERIAL:A compound of formula I (A is carbonyl, hydroxymethylene; R1 is 1W10C alkyl, 5W6-membered cycloalkyl; R2 is H, 1W10C alkyl; R3, R4 and H, protecting group; R5 is H, hydroxy; broken lines means single or double bonds) and its...  
JPH0115517B2
Compounds of the formula wherein R is phenyl cyclohexyl or lower alkyl containing 1-6 carbon atoms; R'' is hydrogen or methyl; R''' is alkenyl or alkynyl having 3-5 carbon atoms; R' is hydrogen, tetrahydrofuran-2-yl tetrahydropyran-2-yl ...  
JPH0114910B2  
JPS6411620B2
Novel 7-hydroxyprostaglandins E1, or stereoisomers thereof, or protected derivatives thereof, having the following formula: …… wherein R<8> represents H, CH3 or C2H5, R<9> represents H or CH3, R<1><0> and R<1><1> are identical or dif...  
JPS6411018B2  
JPS646181B2
This disclosure describes novel 2,5-dihydro-2,5-dialkoxyfuran derivatives useful as intermediates for the preparation of the natural prostaglandins and their congeners.  
JPS6366832B2
4,5-Unsaturated 16-hydroxy prostanoic acid derivatives displaying valuable pharmacological properties, e.g. gastric antisecretory, are described herein.  
JPS63287747A
The present invention relates to allenic prostacyclin derivatives of the formula: wherein: n is 0, 1,2 R<1> is hydrogen, lower alkyl, lower hydroxyalkyl, or a pharmaceutically acceptable cation; R<2> is hydrogen, lower alkyl, cycloalkyl,...  
JPS63287751A
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.  
JPS63246331A
Prostaglandin E1 derivatives as pharmacological active compounds and medicaments containing these compounds are described, in particular for transcutaneous application.  
JPS6344743B2
An improved method for the preparation of prostaglandin analogs which comprises preparation of two equivalents of an alkyl or alkenyl lithium reagent in an aprotic solvent mixture such as pentane or hexane and tetrahydrofuran, conversion...  
JPS6344143B2  
JPS6343385B2
PCT No. PCT/JP84/00294 Sec. 371 Date Jun. 11, 1985 Sec. 102(e) Date Jun. 11, 1985 PCT Filed Jun. 7, 1984 PCT Pub. No. WO84/04917 PCT Pub. Date Dec. 20, 1984.7-Fluoroprostaglandins represented by the following formula (I): (I) In the form...  
JPS63502184A
(57) [Abstract] Since this gazette is application data in front of an electronic application, the data of an abstract is not recorded.  

Matches 851 - 900 out of 1,938