| Document |
Document Title |
|
WO/2009/043784A1 |
Compounds of the formula (I) wherein Ar1, Ar2, R1 and R2 are as defined herein. Also provided are pharmaceutical compositions, methods of using, and methods of preparing the subject compounds.
|
|
WO/2009/040952A1 |
Because of having an effect of inhibiting RANKL production, an effect of inhibiting lowering in OPG production and an effect of inhibiting the differentiation and activation of osteoclasts, a drug characterized by containing a benzopheno...
|
|
WO/2009/035004A1 |
Disclosed is a novel pest control agent, especially an insecticide or a miticide. Specifically disclosed is a substituted isoxazoline compound represented by the general formula (1) of claim 1 (wherein A1, A2 and A3 independently represe...
|
|
WO/2009/035949A2 |
Disclosed are heterocylic or heteroaryl compounds of Formula I and compositions that inhibit soluble epoxide hydrolase (sEH), methods for preparing the compounds and compositions, and methods for treating patients with such compounds and...
|
|
WO/2009/028727A1 |
There is provided a fluorine-containing organosulfur compound having an excellent controlling effect on arthropod pests represented by the formula (I): wherein m represents 0 or 1; n represents 0, 1 or 2; A represents an optionally subst...
|
|
WO/2009/027450A1 |
The invention relates to compounds of general formula (I), in which n, R1, R2, R3, R4, R5, R6, R7 and R8 are defined as cited in the description, to the enantiomers, diastereomers, mixtures and salts of said compounds, in particular to t...
|
|
WO/2009/026658A1 |
The present invention relates to PPAR agonists and their use in therapy, including the treatment of disease. In particular, the invention relates to compounds which are PPAR-gamma agonists and/or PPAR alpha/gamma dual agonists.
|
|
WO/2009/028655A1 |
Disclosed is a heterocyclic compound having a strong Raf inhibitory activity. Specifically disclosed is a compound represented by the formula (I) below or a salt thereof. (I) (In the formula, the symbols are as defined in the description.)
|
|
WO/2009/025983A2 |
Disclosed is a method for preparing a compound of Formula: (1); wherein R1 is CHX2, CX3, CX2CHX2 or CX2CX3; each X is independently Cl or F; Z is optionally substituted phenyl; and Q is phenyl or 1-naphthalenyl, each optionally substitut...
|
|
WO/2009/024550A1 |
The present invention relates to N-benzyl,N' -arylcarbonylpiperazine derivatives having the general Formula (I) to pharmaceutical compositions comprising the same, and to the use of a these N-benzyl,N' -arylcarbonylpiperazine derivatives...
|
|
WO/2009/022746A1 |
Disclosed is a nitrogen-containing heterocyclic compound represented by the formula (I) below or a salt thereof. Also disclosed is a pest control agent containing such a compound or a salt thereof as an active ingredient. (In the formula...
|
|
WO/2009/016241A1 |
The present invention relates to isoxazole-3-carboxamide derivative having the general Formula (I), or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of said isoxazol...
|
|
WO/2009/012954A1 |
The invention provides a compound of formula (I) or a pharmaceutically acceptable ester, amide, solvate or salt thereof, including a salt of such an ester or amide, and a solvate of such an ester, amide or salt, wherein W, X, Y, Z, R1, R...
|
|
WO/2009/011850A2 |
Disclosed herein are novel compounds of Formula (I), wherein the variables are defined as herein. The compounds of Formula (I) are useful as kinase inhibitors and as such would be useful in treating certain conditions and diseases, espec...
|
|
WO/2009/010784A1 |
Compounds of formula (I): wherein the substituents are as defined in the specification, are described and claimed. The invention further relates to pharmaceutical compositions containing said compounds and to the use of said compounds in...
|
|
WO/2009/012312A1 |
Compounds that inhibit Aurora-kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.
|
|
WO/2009/012283A1 |
Compounds of formula I active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases. Formula (I) wherein Ar is optionally substi...
|
|
WO/2009/012125A1 |
Compounds of formula (I): formula (I) wherein variables are as defined herein and their pharmaceutical compositions and methods of use are disclosed as useful for treating dyslipidemia and diseases related to dyslipidemia.
|
|
WO/2009/005015A1 |
Disclosed is a novel pest control agent, in particular a pesticide or a miticide. Specifically disclosed are a substituted isoxazoline compound or a substituted enone oxime compound represented by the general formula (1) below or the gen...
|
|
WO/2009/003719A2 |
The present invention relates to indane-amine compounds of general formula (I), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a medicament for the treatment of humans or...
|
|
WO/2009/002809A2 |
Disclosed are compounds of Formula (I), wherein R1 is halogen, C1-C2 haloalkyl or C1-C2 haloalkoxy; R2 is H, halogen or cyano; R3 is H, halogen or CF3; R4 is H, C2-C7 alkylcarbonyl or C2-C7 alkoxycarbonyl; and R5 is C1-C6 alkyl or C1-C6 ...
|
|
WO/2009/001942A1 |
[PROBLEMS] To provide a novel intermediate for the production of a harmful organism control agent. [MEANS FOR SOLVING PROBLEMS] [Chemical formula 1] Disclosed are: a method for producing a 1,3-bis(substituted phenyl)-3-substituted-3-hydr...
|
|
WO/2008/156142A1 |
It is intended to provide a novel compound which has AT2 receptor agonism and is capable of being expected as a pharmaceutical and to provide a therapeutic or preventive method for various diseases. A novel malonic acid sulfonamide deriv...
|
|
WO/2008/156601A1 |
The present invention provides tricyclic compounds according to formula (I): (I) where R1, R2, R3, W, X, Y, Z, m, n, and p are as defined in the description; as well as pharmaceutical compositions comprising the same, methods of use of t...
|
|
WO/2008/154528A2 |
Disclosed are compounds of Formula I, including all geometric and stereoisomers, N-oxides, and salts thereof. Also disclosed are compositions containing the compounds of Formula I and methods for controlling an invertebrate pest comprisi...
|
|
WO/2008/152081A2 |
The present invention is concerned with novel anthelmintic N-benzo[d]isoxazol-6-yl-benzamide derivatives and the pharmaceutically acceptable acid addition salts thereof, compositions comprising said novel Compounds, processes for prepari...
|
|
WO/2008/150231A1 |
The present invention relates to new compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein Q, X, Y, A, R1, R2, R3, R4, R5, R6 and m, n, and p are defined as in claim 1, processes for their preparation and to new ...
|
|
WO/2008/142134A1 |
This invention relates to novel benzisoxazole derivatives that are found to be potent modulators of potassium channels and, as such, are valuable candidates for the treatment of diseases or disorders as diverse as those which are respons...
|
|
WO/2008/130651A2 |
The invention disclosed in this document is related to field of pesticides and their use in controlling pests. The inventive compounds have the general formula.
|
|
WO/2008/130514A1 |
The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula (I) where the definitions of the variables are provided herein. The present invention al...
|
|
WO/2008/126665A2 |
An isoxazoline compound represented by the formula (I): wherein the substituents are as defined in the description, has a controlling activity against pests.
|
|
WO/2008/125014A1 |
The urea compounds of formula I, pharmaceutically acceptable salts and solvates, their preparation methods, the pharmaceutical compositions comprising the said compounds and the uses as p38 kinase inhibitors thereof. The substituents are...
|
|
WO2008035315A9 |
The present invention relates to catechol derivatives of formula I, which can be used as inhibitors of phosphodiesterase (PDPI) type 4 or type 7, Compounds disclosed herein can be useful in the treatment of CNS disorders, inflammatory di...
|
|
WO/2008/126772A1 |
Disclosed is a novel therapeutic agent for prehypertension or hypertension, which has a different xanthine oxidase inhibitory activity from that of a conventional hypotensive agent used in clinical practice, and which is more effective c...
|
|
WO/2008/123349A1 |
Disclosed is an N-phenyl-N'-phenylsulfonylpiperazine derivative. Also disclosed is a method for efficiently producing an intermediate for the N-phenyl-N'-phenylsulfonylpiperazine derivative. Specifically disclosed is a method for produci...
|
|
WO/2008/122357A1 |
The present invention relates to 5-oxo-isoxazole derivatives of the general formula (I) with the meanings disclosed in the description, the pharmaceutically applicable salts thereof, and the use thereof as drugs.
|
|
WO/2008/122787A1 |
The present invention relates to compounds of general formula (I): wherein A, Y, X, n and B are as defined herein; and their use in the treatment and prevention of metabolic disorders, inflammatory conditions, allergic conditions, fever,...
|
|
WO/2008/122375A2 |
The present invention relates to novel aryl isoxazoline derivatives having excellent insecticidal activity as insecticides and represented by the formula ( I ): and their use as insecticides and acarizides.
|
|
WO/2008/123469A1 |
Disclosed is a compound having excellent SCD1 activity inhibitory action. Specifically disclosed is a compound represented by the general formula [B-0'] below, a pharmaceutically acceptable salt thereof, or a solvate thereof. [B-0'] (In ...
|
|
WO/2008/116663A2 |
The present invention relates to heterocyclyl-substituted-tetrahydro-naphtalen-amine compounds of general formula (I) methods for their preparation, medicaments comprising these compounds as well as their use for the preparation of a med...
|
|
WO/2008/109334A1 |
A novel crystalline anhydrous toluenesulfonic acid salt form of a selective PPAR gamma partial agonist which has a fused bicyclic aromatic group attached to an oxypropanoic acid moiety is stable and non-hygroscopic. The crystalline salt ...
|
|
WO/2008/109027A2 |
Cannabinoid derivatives according to formula (I) are disclosed wherein, X, Y, R1, R2, and W can have the definitions provided herein. Without limitation, use of such compounds, their salts or pro-drug, or compositions containing the comp...
|
|
WO2004078116A9 |
This invention relates to inhibitors of p38, and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors of the invention and methods of utilizing the inhibitors and pharm...
|
|
WO/2008/108448A1 |
Disclosed is a novel pest control agent, particularly an insecticide or a miticide. Specifically disclosed is an isoxazoline-substituted benzamide compound represented by the general formula (1) (which is expressed as [chemical formula 1...
|
|
WO/2008/104994A2 |
Compounds of the present disclosure are 2,2,2-tri-substituted acetamide derivatives of formula (I), its polymorphs, stereoisomers, prodrugs, solvates, pharmaceutically acceptable salts and formulations thereof, useful as Glucokinase acti...
|
|
WO/2008/102908A1 |
Disclosed is a novel herbicide. Specifically disclosed is a haloalkylsulfonanilide derivative represented by the general formula (1) below, or an agrochemically acceptable salt thereof. (In the formula, Q represents -N(R5)SO2R6, wherein ...
|
|
WO/2008/095689A1 |
The present invention relates to heterocyclyl-substituted-tetrahydro-naphthalen compounds of general formula (I) and (I prot), methods for their preparation, medicaments comprising these compounds as well as their use for the preparation...
|
|
WO/2008/089459A1 |
This invention concerns to N-(2-aylamino) aryl sulfonamides, which are inhibitors of MEK, methods of using such compounds in the treatment of hyperproliferative diseases, and to pharmaceutical compositions containing such compounds.
|
|
WO/2008/084872A1 |
Disclosed is a hydrazone derivative represented by the formula [I] below or a pharmacologically acceptable salt thereof, which is useful as a glucokinase activator. (In the formula, ring A represents an aryl or a heteroaryl; T represents...
|
|
WO/2008/080455A1 |
Compounds of Formula (I), in which A1, A2, R1, X1, X2, X3, Y, R2, Cy, and n have the meanings set forth in claim 1, can be used, among other things, for the treatment of tumors.
|
