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Matches 851 - 900 out of 2,762

Document Document Title
WO/1981/002427A1
Process for the fermentation of bile which includes the step of cultivating one or more aerobic microorganisms which have the ability to selectively degrade bile acids or bile acid conjugates contained in bile. The fermentation is carrie...  
WO/1981/002298A1
New derivative of vitamin D, 25-hydroxy-26,26,26,27,27,27-hexafluoro cholecalciferol and process for preparing the same. The compound is characterized by vitamin D-like activity in their ability to increase intestinal calcium transport, ...  
WO/1980/002502A1
New vitamin D derivatives as well as new intermediate compounds derived during the processes for preparing such new derivatives. The new derivatives have been identified as 1(Alpha)-hydroxy-25-keto-27-nor-vitamin D3 and its acylates. 1(A...  
WO/1980/002562A1
Isotopically labeled vitamin D compounds, including radiolabeled vitamin D compounds of high specific activity, methods for their preparation, and novel intermediates in their synthesis. The radiolabeled vitamin D compounds are character...  
WO/1980/002098A1
Isoflavones and related compounds useful as antioxidants and in antioxidant compositions including edible fats and oils. Many of these compounds can be recovered from tempeh, a fermented soybean product, Others can be prepared by chemica...  
WO/1980/002027A1
Ergostadientriols which may be recovered from either the fungus R. oligosporus or the fungus R. oryzae as well as from soybeans which have been fermented with either of these fungi. Alternatively, the sterols may be chemically synthesize...  
WO/1980/001915A1
New derivative of vitamin D3,24,24-difluoro-25-hydroxycholecalciferol. The compound is characterized by vitamin D-like activity in its ability to increase intestinal calcium transport, increase serum calcium and inorganic phosphorous con...  
WO/1979/000513A1
The principal object of the invention is to provide a method for directly introducing an oxygen function at carbon 1 of the vitamin D molecule or precursors or derivatives thereof which comprises subjecting such molecule to allylic oxida...  
JP2024040444A
[Problem] To provide a method for treating a disease. The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof [where n, R19,R5,R3a,R6a,R6b,R1,R2a,R2b,R4a,R4b,R7a,R7b,R11a,R11b,R12a ,R12b,R17...  
JP2024510146A
The invention particularly relates to methods of producing sulfated oligosaccharide derivatives and intermediates thereof. The sulfated oligosaccharide derivatives have the following formula (I), where X and Y are any D- or L-hexose or p...  
JP2024509902A
The present invention includes a novel amino acid derivative, a method for producing the same, and a method for producing the same.Bhepatitis orDIt relates to a pharmaceutical composition for the treatment of hepatitis type, comprising t...  
JP2024028631A
[Problem] To provide oxysterols and methods for using the same. [Solution] Formula (I): and pharmaceutically acceptable salts thereof and pharmaceutical compositions thereof are provided, wherein R2,R3,R4,R5, and R6is as defined herein. ...  
JP2024020310A
The present invention provides a method for producing mogrol glycosides and other triterpenoid compounds using recombinant microbial host cells. The present invention provides mogrol, including minor products of Siraitia grosvenorii, mog...  
JP2024019459A
[Problem] To provide a new compound Disclosed herein are novel compounds, pharmaceutical compositions containing such compounds, and related methods of use thereof. The compounds described herein are useful, for example, as liposomal del...  
JP2024505449A
This disclosure describes compositions, preparations, nanoparticles (such as lipid nanoparticles), and/or nanomaterials, and methods of using them.  
JP2024001871A
An object of the present invention is to provide a salt, an acid generator, a resist composition, etc. that can produce a resist pattern with good CD uniformity. A salt represented by formula (I), an acid generator, and a resist composit...  
JP2024001870A
An object of the present invention is to provide a carboxylic acid salt, a resist composition, etc., which can produce a resist pattern having good resistance to pattern collapse. A carboxylic acid salt represented by formula (I), a carb...  
JP7410062B2
Compounds are provided according to Formula (I):and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein R1, R2, R3, R4, R5, and R8 are as defined herein. Compounds of the present invention are cont...  
JP7382946B2
The present invention provides host cells and methods for making mogrol glycosides, including Mogroside V (Mog. V), Mogroside VI (Mog. VI), Iso-Mogroside V (Isomog. V), and glycosylation products that are minor products in Siraitia grosv...  
JP7375685B2
A chemically amplified resist composition comprising a quencher containing an ammonium salt of a carboxylic acid having an iodized or brominated hydrocarbyl group exclusive of an iodized or brominated aromatic ring and an acid generator ...  
JP7365082B2
The present invention discloses a synthesis method of ursodeoxycholic acid by using the plant-derived compound BA as a raw material to synthesize ursodeoxycholic acid through the steps of ethylene glycol or neopentyl glycol protection, o...  
JP7361715B2
Provided is a method for producing high-purity cholesterol which does not contain a substantial amount of desmosterol, said method comprising reacting cholesterol mixed with desmosterol with a halogenating reagent and water and then sepa...  
JP7344983B2
The present invention relates to a method for preparing a chenodeoxycholic acid derivative. Particularly, disclosed is a method for carrying out one-pot reduction on a compound represented by Formula (VI), i.e., 3α-hydroxyl-ethidene-7-k...  
JP2023126904A
To provide new oxysterols that modulate an NMDA receptor for the prevention and treatment of conditions associated with the NMDA expression and function.The invention provides compounds according to Formula (I) in the figure, and pharmac...  
JP2023538133A
Prodrugs that target the low-density lipoprotein receptor (LDLR) and contain acid- and/or enzymatically-cleavable acetal- or oxybenzyloxy-linked carbonate or carbamate linkages are described. Also described are core-shell nanoparticles c...  
JP2023536515A
Regarding prodrugs of ester derivatives of inotodiol and their uses, said prodrugs not only have increased solubility in inorganic and organic solvents, but also have improved stability to treat various inflammations, including inflammat...  
JP2023111289A
To provide new lithocholic acid derivatives with sufficient vitamin D3 activity.The invention provides a compound represented by the general formula (I) in the figure, a salt thereof, or a prodrug thereof. (In the formula, R1 and R2 each...  
JP7317898B2
Compounds are provided according to Formula (I):and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein R1, R2, R3a, R3b, R4, R5a, R5b, R6a, and R6b are as defined herein. Compounds of the present ...  
JP2023104925A
To provide novel solid forms (e.g., crystalline forms) of berberine ursodeoxycholate (BBR-UDCA) having one or more desirable properties, such as high stability, high crystallinity, high purity, low hygroscopicity, favorable dissolution p...  
JP7311921B2
The present invention relates to the field of pharmaceutical chemistry, and specifically to a method for preparing cholesterol, a derivative thereof, and an analog thereof. The derivative of cholesterol comprises, but is not limited to, ...  
JP7308886B2
Compounds are provided according to Formula (I), and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein A, R1, and R5 are as defined herein. Compounds of the present invention are contemplated use...  
JP7308811B2
The present invention falls within the field of pharmaceutical chemistry, and relates to a method for preparing a steroid derivative FXR agonist and relevant intermediates. In particular, the present invention relates to a method for pre...  
JP7304444B2
Compounds are provided according to Formula (A):and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof; wherein R1, R2, R3, R4, R5, R6, and RG are as defined herein. Compounds of the present invention are ...  
JP2023527736A
A structure of formula I, II or III, R.1~R18at least one of (e.g. R3, R7and R12) is a cationic steroid antibacterial (CSA) compound, or a salt thereof, having a structure linked to a steroidal backbone by a urethane group. R.1~R18at leas...  
JP7286615B2
The invention relates to a process for the preparation of obeticholic acid and derivatives thereof comprising: (a) hydrogenation of the double bond and reductive opening of the epoxide of a compound of formula (II) or a salt or solvate t...  
JP2023520668A
The present invention relates to nanoparticles containing drug dimers and uses thereof. Nanoparticles containing drug dimers of the present invention can increase drug content and improve drug dispersibility. In addition, the nanoparticl...  
JP2023063535A
The present invention relates to oxysterols and methods of using them. [Solution] Formula (A): and pharmaceutically acceptable salts thereof and pharmaceutical compositions thereof, wherein R1, R2, R3, R4, R5, R6and RG.is as defined here...  
JP2023062677A
To provide a chemically amplified resist material which exhibits high sensitivity and improved LWR and CDU regardless of whether it is positive or negative, and a pattern forming method using the same.The chemically amplified resist mate...  
JP2023518411A
As used herein, formula (I): [In the formula, R2a, R2b, R3, R4a, R4b, R5, R6a, R6b, R11a, R11b, R15a, R15b, R16a, R16b, R18, R19, R20a, R20b, X, A, Z, q, u, r, s, t, m, and n are as defined herein] or a pharmaceutically acceptable salt t...  
JP7260098B2
The present invention relates to a cocrystal of beta-sitosterol or a pharmaceutically acceptable ester thereof or an edible acceptable ester thereof and an organic carboxylic acid coformer, an hydrate crystal form of beta-sitosterol havi...  
JP7258466B2
Use thereof in electro-optical displays, particularly in active-matrix displays based on the VA, ECB, PALC, FFS or IPS effect and use of compounds of formula I for stabilisation of liquid-crystalline media which comprise one or more comp...  
JP2023513086A
GCPII inhibitors comprising 2-(phosphonomethyl)pentanedioic acid (2-PMPA) conjugated to bile acids and their use to treat diseases or conditions associated with elevated GCPII levels, such as inflammatory bowel disease.  
JP2023040180A
To provide new and improved neuroactive steroids that modulate brain excitability for the prevention and treatment of CNS-related conditions.The invention provides compounds represented by formula (I) and pharmaceutically acceptable salt...  
JP2023508985A
Crystalline and liquid crystalline forms of 25HC3S sodium are described herein. The present disclosure includes 25HC3S sodium Forms I, II, III, V, IX, XI and XIII, and combinations thereof. Pharmaceutical formulations of the above forms ...  
JP7224307B2
The present disclosure relates to methods and novel intermediates useful in the preparation of a compound of formula Ior pharmaceutically acceptable salt, hydrate, solvate or amino acid, sulfate or glucuronide conjugate, or prodrug thereof.  
JP2023022187A
To provide compositions and methods for treating CNS disorders.Described herein are neuroactive steroids of the formula (II) in the figure or pharmaceutically acceptable salts thereof. Such compounds are supposed, in certain embodiments,...  
JP2023503054A
Co-crystals of a compound of formula (I) or a compound of formula (II) and a hydrogen bond donor coformer that is a phenolic compound are provided. Compositions comprising the co-crystals and personal care products comprising the composi...  
JP7208420B2
The invention discloses a method for fluoroalkylation of enamines with a fluoro alkyl halide in the presence of a base.  
JP7202646B2
To provide extraction methods capable of separating and recovering oryzanol in high yield from cereals, miscellaneous cereals and fractions thereof.An extraction method of oryzanol comprises: a first extraction step of adding a raw mater...  
JP7200657B2
To provide a low environmental load material having a protective coating layer, which may be produced using a natural product by a process providing a less environmental load relatively to various molding processes, and is compatible of ...  

Matches 851 - 900 out of 2,762