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WO/2023/153890A1 |
A scaffold thin film used as a membrane undergoes dried and swollen states during the manufacturing, selling, purchasing, and use thereof. The resultant deformation, such as creases, may have a negative influence during the use of the th...
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WO/2023/153413A1 |
Provided is a system for predicting the proportion of target cells in cultured cells containing two or more types of cells, said system including an analysis unit for predicting the proportion of the target cells on the basis of the prop...
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WO/2023/152487A1 |
There is provided a method of culturing cells comprising: providing a bioreactor, wherein the bioreactor contains a particulate substrate arranged as a fixed bed; seeding the particulate substrate with myoblasts, myocytes, and/or myotube...
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WO/2023/152492A1 |
There is provided a method of culturing cells, the method comprising: obtaining a substrate assembly, the substrate assembly comprising: (i) a plurality of fibres, wherein each fibre has an internal channel running along its length; (ii)...
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WO/2023/153401A1 |
[Problem] Conventionally, it has been known that the production efficiency of platelets can be optimized by agitating contents under the agitation condition that the shear force index is a predetermined value. By utilizing this, the pres...
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WO/2023/154874A2 |
A method can include receiving a biological sample including the target cells, e.g., at an inlet of a microfluidic structure. This can involve flowing the target cells, e.g., suspended in a first buffer, at a first flow rate within a mai...
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WO/2023/152493A1 |
There is provided a substrate assembly for culturing cells, wherein the substrate assembly comprises: a plurality of edible fibres, wherein each fibre has an internal channel running along its length; a first support at a first end of th...
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WO/2023/152145A1 |
A pH system that is able to compensate for variations in pressure and conductivity is disclosed. The system includes a pH sensor, a pressure sensor and optionally a conductivity sensor, the outputs of each are transmitted to a controller...
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WO/2023/151185A1 |
The present application relates to the technical field of nucleic acid extractors, and provides an automatic nucleic acid extractor, comprising a base, a sample container module arranged on the base, a slide rail mechanism arranged on th...
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WO/2023/154280A1 |
A biological sample collection system and dispensing system is described. The biological sample collection system provides for collection and processing of a biological sample (i.e. bodily fluids collected from nose, throat, or other muc...
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WO/2023/153415A1 |
In the present invention: image data of a sheet-like cell culture is acquired as time passes; and the separation of the sheet-like cell culture from the culture substrate is automatically detected by analyzing changes over time in the ac...
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WO/2023/151260A1 |
A cell culture flask, comprising a cell culture flask body and a flask cap, wherein the flask cap is connected to the cell culture flask body by means of a thread. The cell culture flask further comprises a flask cap fixing device, the f...
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WO/2023/151877A1 |
The invention relates to reactors comprising at least three flow regions arranged concentrically around one another or in layers on top of one another, each separated from one another by membranes, comprising at least two fluid supply de...
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WO/2023/152488A1 |
There is provided a method of culturing cells, wherein the method comprises: placing a substrate in a bioreactor, wherein the substrate is in the form of a rolled-up film; culturing cells on the substrate in the bioreactor; and optionall...
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WO/2023/153849A1 |
The present invention relates to a cell culture device, a cell culture system comprising same and a manufacturing method therefor. Particularly, the present invention provides a cell culture device and a manufacturing method therefor, th...
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WO/2023/147988A1 |
The present invention relates to a bioreactor for producing a biological medicament from a biological liquid that originates from a sample taken from a patient or a donor, characterized in that the bioreactor is composed of two flexible ...
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WO/2023/150717A1 |
An analytical instrument having a sensing system, a stage adapted to receive a sample carrier, a motion actuator assembly for positioning the sensing system and/or the stage, a temperature control element, and a signal processing module ...
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WO/2023/149235A1 |
In the present invention, with regards to a cell production method, in particular for a system in which a carrier is suspended and oscillated in a culture liquid, provided is a method capable of reducing the physical stress imposed on an...
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WO/2023/148244A1 |
The present invention relates to a method for detecting and/or quantifying at least one microorganism in a sample by encapsulating the sample with a fluorescent dye into water- in-oil emulsion droplets using a microfluidic device, incuba...
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WO/2023/150597A2 |
Disclosed herein a robust approach to monitor cell interactions with its surrounding environment in real-time in a physiologically relevant 3-D microenvironment, holding great promise for enhancing future studies of detecting and monitor...
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WO/2023/150268A1 |
A calibrator bottle and method of calibration. The calibrator bottle includes a plastic material that is doped or compounded with a fluorescent material system that fluoresces in a target range and may be used to calibrate a blood cultur...
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WO/2023/148524A1 |
Adipose tissue lipoaspirated or removed from the body, containing mesenchymal stem cells, obtained with a method for promoting the anti- inflammatory properties and for improving the repairing capability, comprising a step of mechanical ...
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WO/2023/147908A1 |
In a device (1) and a method for examining and processing a biological or medical sample, a dispensing unit (3) serves to dispense the sample into a depression of a sample holder (10). The sample holder (10) has an aspect ratio of the he...
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WO/2023/150574A1 |
Systems, devices, and methods for growing, transporting, and deploying large quantities of carbon-rich marine species such as macroalgae, microalgae, kelp, and/or plankton into the open ocean from vessels and/or ocean platforms are descr...
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WO/2023/147905A1 |
The present invention relates to a method and apparatus for converting carbon monooxide and/or carbon dioxide and hydrogen in a gas to methane and water. The gas comprising carbon monooxide and/or carbon dioxide is preferably a biogas, f...
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WO/2023/147625A1 |
The invention provides a system for pumping a fluid through a target unit, comprising a source of compressed gas, a gas circuit connected to said source of compressed gas and including gas flow control apparatus, a first connection and a...
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WO/2023/150379A1 |
The present disclosure relates to improved biomanufacturing systems and methods with an ability to effectively control process variability to consistently generate high-quality cell-based therapies. In particular, disclosed herein is a u...
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WO/2023/147713A1 |
Disclosed is a combined detection structure for dual sampling and integrated detection. The combined detection structure is a combined set of a saliva sampling structure (2), a nasal-cavity sampling structure (1) and a chromatographic as...
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WO/2023/149291A1 |
Provided is a method for producing a culture vessel that enables the production of a culture vessel which has a culture surface uniformly and stably coated with a cell-adhesive material, while reducing the amount of the cell-adhesive mat...
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WO/2023/149068A1 |
This masking sheet is used for patterning cells or cellular aggregates to be formed on a culture surface. The masking sheet comprises an adhesive layer that is adhered to the culture surface, a support layer that is layered on the adhesi...
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WO/2023/147838A1 |
The invention relates to a process and an apparatus for the biotechnological production of a bioproduct. The process involves a first and second bioprocess carried out in a first and second bioreactor (2, 3), and a vessel (4). The first ...
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WO/2023/149526A1 |
In this particle measurement method, a particle measurement sensor device 300 is used. In the particle measurement sensor device 300, a thin film 200 is in contact with a Si single crystal substrate 290, in which an Si single crystal com...
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WO/2023/141944A1 |
A separation apparatus (100), comprising a separation chip (10, 10'), an oscillation system (70), a differential pressure driving system (50), a frequency conversion module (40) and a controller (60). The separation chip (10, 10') compri...
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WO/2023/145208A1 |
Provided is a fluid handling device that can fill a fluid into not only a specific flow path, but also a connecting flow path branching therefrom. This fluid handling device has a main flow path, a first flow path, and a first connecti...
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WO/2023/146249A1 |
A cranial nerve modeling device for mimicking a brain micro-environment, according to one embodiment, is disclosed. The cranial nerve modeling device comprises: a microfluidic chip including a plurality of cell culture channels, and elec...
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WO/2023/146209A1 |
According to the present invention, a smart interactive print bed for a new innovative bio-printer capable of generating different external but controllable energy waves is designed and implemented to induce the growth of cells using a b...
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WO/2023/142260A1 |
An on-chip microgroove array digital PCR chip based on electrical impedance detection, comprising a microgroove array, a power supply module, a clock generation module, a digital control logic module, a driving module, an analog-to-digit...
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WO/2023/142280A1 |
An easily cleaned PCR tester, comprising a tester box and a positioning plate provided in the tester box, wherein the positioning plate is provided with an insertion hole; a heating water bag is provided in the tester box, and the heatin...
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WO/2023/143198A1 |
A deep-bed filtering medium and a preparation method therefor. The deep-bed filtering medium comprises a filtering medium body, which comprises fibers and a filter aid, wherein the fibers comprise crude fibers and superfine nanofibers; t...
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WO/2023/143526A1 |
A marker capturing device, comprising a sleeve assembly and a magnetic assembly. The sleeve assembly comprises an outer sleeve (1) and an attachment sleeve (2) provided in the outer sleeve (1), and the outer surface of the attachment sle...
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WO/2023/145961A1 |
Provided is an IGF1R CAR-T cell that is expected to be effective against tumors that express IGF1R. Provided is a polynucleotide that encodes a chimeric antigen receptor (CAR) protein having a target-binding domain that binds to the insu...
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WO/2022/140344A9 |
The present disclosure provides materials and methods identifying, selecting, and characterizing cells that express and secrete non-Fc containing biomolecules.
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WO/2023/145689A1 |
[Problem] In a glycated protein sensor including an immobilized enzyme, it is essential to develop a technique for enhancing the accuracy of measurement and the stability of the glycated protein sensor. However, an enzyme capable of enha...
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WO/2023/141916A1 |
The present disclosure provides a chip heat dissipation apparatus and a nucleic acid extraction device. A chip is provided with a channel used for conveying a fluid, and on-off of the channel is controlled by means of an electromagnetic ...
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WO/2023/145624A1 |
The present invention estimates intestinal information for a subject with high accuracy from components contained in gas generated from excrement of the subject. The present invention comprises: a detection unit that detects a predetermi...
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WO/2023/144933A1 |
Provided is a cell culture vessel suitable for improving problems occurring in perfusion culture in a closed system. The cell culture vessel is equipped with: a bottomed cylindrical vessel body 1 that has an opening 110 at one end x1 i...
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WO/2023/145797A1 |
A cell detachment method for imparting vibration to cells bonded to a substrate to thereby detach the cells from the substrate, wherein the method is characterized by having an incubation step for incubating the cells after bringing a su...
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WO/2023/144266A1 |
A system for biomass sensing includes a fixed bed bioreactor including a container and a fixed bed disposed within such container. At least one sensor is for sensing one or more parameters representative of biomass in the fixed bed. A co...
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WO/2023/146456A1 |
A material mixing cartridge for a dispensing system comprises a dispensing chamber, with a material dispensing outlet and a dispensing actuator for dispensing material through the material dispensing outlet. The mixing cartridge further ...
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WO/2023/146870A1 |
Systems and methods related to microfluidic devices (e.g., microfluidic devices comprising layers of films) are generally described. In some embodiments, a microfluidic device comprises a substrate configured to facilitate fluid transpor...
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