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Matches 1 - 50 out of 1,961

Document Document Title
WO/2021/086978A1
Microparticles and nanoparticles made of various materials that are used in various configurations are disclosed. The particles may be perfluorocarbon droplets with a lipid coating. The particles may be used in an acoustic cell selection...  
WO/2021/070617A1
Provided is an indirect extraction method, wherein a long-chain biopolymer is extracted from captured cells. This biopolymer extraction apparatus is characterized by comprising a cell capture part which has a film structure and in which ...  
WO/2021/071413A1
A yeast cell for use in the treatment and/or alleviation of allergy and/or symptoms caused by allergy, wherein the yeast cell has been treated with electromagnetic waves in the range of 1 GHz to 300 GHz, or said yeast cell has been grown...  
WO/2021/064244A1
There is provided a process for the separation of molecules from a suspension comprising cells at a concentration of at least 56 x 106 cells/ml, comprising the steps of: a) providing magnetic particles having a specific interaction with ...  
WO/2021/030145A3
The present disclosure provides a system for functional ultrasound imaging, where the system comprises: a) an apparatus for delivering a nucleic acid encoding a mechanosensitive ion channel to a target neural cell population in a region ...  
WO/2021/048550A1
The invention relates to a method for the transformation of host cells of a biofilm with heterologous nucleic acid, wherein the host cells are within the extracellular matrix of the biofilm, the method comprising: adding the heterologous...  
WO/2021/032179A1
Provided is an application of a Pseudomonas aeruginosa vaccine in preventing and treating bacterial infections associated with a burn or scald injury. The burn or scald injury comprises a burn or a scald. The degrees of burn injury compr...  
WO/2021/035009A1
A method of analyzing a sample comprising one or more species of microorganisms can include generating first droplets such that each of one or more microorganisms of a first portion of the sample is encapsulated within one of the first d...  
WO/2021/034990A1
A method and system of sensitization of cancerous cells such as melanoma cells by a nano-pulsed magnetic field is disclosed. The system includes a magnetic field generator to generate a nano-pulsed magnetic field directed at the area hav...  
WO/2021/030292A1
A method for making an acellular human amnion-derived composition configured for therapeutic use is disclosed and generally includes the steps: obtaining amniotic membrane tissue; testing the amniotic membrane tissue for pathogens; washi...  
WO/2021/025388A1
The present invention pertains to: an exosome derived from irradiated cancer cells; a pharmaceutical composition containing mature dendritic cells obtained using same; and a method for producing same. Provided are: a method for producing...  
WO/2021/021829A1
Systems, devices, and methods for producing a tissue specimen and performing subsequent biomechanical testing thereof to quantify various biological/physiological properties and characteristics. The system may include a bioreactor device...  
WO/2021/020694A1
The present invention relates to an electric fusion needle for producing somatic cell nuclear transfer embryos using an easily replaceable platinum wire, the electric fusion needle being characterized in that a ball of a replacement part...  
WO/2021/007170A1
Provided herein are improvements in cell culture methods and compositions related thereto. In partial particular, provided herein are compositions and methods, and kits increasing the cellular division times and viability. Also provided ...  
WO/2021/003451A1
Devices, systems, and kits for cell transfection are provided. A device includes a first electrode, a second electrode, and an electroporation zone therebetween where an electrical potential difference applied to the first and second ele...  
WO/2020/257866A1
A method for transforming a cell with a nucleic acid molecule, comprising applying a voltage to a solution comprising (i) the cell; (ii) the nucleic acid molecule; (iii) a leading electrolyte; and (iv) a terminating electrolyte; wherein ...  
WO/2020/263533A1
A method of identifying a lead or candidate compound that modulates the activity of GTPase-Activating Protein SH3 Domain-Binding Proteins (G3BP) is provided, which includes determining whether a compound modulates the interaction between...  
WO/2020/256520A1
The present invention relates to a method for producing exosomes by electrical stimulation and, more specifically, to a method for producing exosomes, comprising the steps of: (a) applying radio wave electrical stimulation to cells and c...  
WO/2020/249616A1
A method of upregulating the synthesis of pyruvate and/or a metabolite of pyruvate in a photosynthetic microorganism, a method for the photosynthetic production of a one, two, three or four carbon compounds, and a method for the producti...  
WO/2020/232437A1
Disclosed are a system, device, and method for the electroporation of cells. Systems, devices and methods for electroporation of living cells and the introduction of selected molecules into the cells utilizes a fluidic system where livin...  
WO/2020/146702A3
The present disclosure relates to methods of stimulating cell proliferation, promoting differentiation of cells, regenerating cells, promoting nodule formation, and promoting myotube formation. The methods include applying one or more pu...  
WO/2020/210023A1
CAR T cell therapies have shown promise in treating human blood cell cancer. The preparation of CAR T cells involves many complex, time consuming steps prior to infusion of the CAR T cells into a cancer patient. One step in the process t...  
WO/2020/210458A1
Methods of using pulsed focused ultrasound (pFUS) therapy to treat pancreatic disorders such as type 1 diabetes, pancreatitis, and pancreatic cancer are provided. The methods utilize pulsed focused ultrasound (pFUS) therapy either by its...  
WO/2020/205862A1
An apparatus includes multiple first reservoirs and multiple second reservoirs joined with a substrate. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multipl...  
WO/2020/185622A1
Described is a low voltage, pulsed electrical stimulation device for upregulating expression of klotho, a useful protein, by tissues. Also described are methods of enhancing expression of klotho in cells.  
WO/2020/183984A1
The present invention addresses the problem of providing a method for introducing a substance into a protoplast or an alga by electroporation under novel voltage applying conditions. The problem can be solved by a method for introducin...  
WO/2020/177456A1
Mutagenesis is carried out on hyaluronidase-producing Lactobacillus plantarum to obtain a high hyaluronidase-producing mutant strain of Lactobacillus plantarum CnT012-56, the accession number being: CGMCC NO.16836. Lactobacillus plantaru...  
WO/2019/140019A8
A closed and modular fluidic system composed of one or more acoustic elements and cell processing reagents. The system employs a cellular manufacturing process for producing cell and gene therapy therapeutics.  
WO/2020/171783A1
The present invention proposes a system (100) for subjecting a group of cells placed onto a surface (s1) of a vessel (4) when such vessel (4) is introduced into the system (100) and then the system (100) is run, to magnetofection using a...  
WO/2020/161942A1
This growth promotion method promotes the growth of an organism. An organism disposed in a growth environment has imparted thereto a 0.5-1000MHz high frequency AC electrical field having a frequency band such that water dielectric loss b...  
WO/2020/160501A1
Systems and methods described herein employ focused acoustic energy applied to a reservoir containing a fluid to eject a fluid sample from the fluid sample reservoir, e.g. to an inlet of an analytical device. In many embodiments, the eje...  
WO/2020/145426A1
The present invention relates to a method for preparing a live attenuated vaccine by radiation and a live attenuated vaccine composition prepared thereby. More specifically, the present invention relates to: a method for preparing a live...  
WO/2020/146702A2
The present disclosure relates to methods of stimulating cell proliferation, promoting differentiation of cells, regenerating cells, promoting nodule formation, and promoting myotube formation. The methods include applying one or more pu...  
WO/2020/130106A1
Provided are: an electroporation device which, compared to devices in which electroporation is performed by reciprocating a solution (liquid droplets) containing a foreign substance and cells in an oil, facilitates an operation for colle...  
WO/2020/125447A1
Provided is a preparation method for an exosome. A cell is stimulated by means of non-invasive ultrasound to regulate the microRNA expression abundance in the cell exosome. The method has good universality, is simple in operation, and ha...  
WO/2020/128908A2
The disclosure provides methods for the selection and isolation of T cells expressing programmed cell death 1 (PD-1) and for selecting a PD-1 expression level of the isolated PD-1 expressing T cells. The disclosure also provides methods ...  
WO/2020/123688A1
The invention, in some aspects, relates to polypeptide molecules and their encoding nucleic acid molecules and use of such molecules to direct and localize sensor molecules in the soma of cells in which they are expressed. Compositions o...  
WO/2020/122702A1
The invention relates to a method for increasing the production of biomass and fatty acids in the alga Chlorella vulgaris Beyerinck and obtaining a biomass rich in lipids of type C:16 (palmitic acid), C18:1n-9 (oleic acid), C18:2n-6t (li...  
WO/2020/080920A3
The present invention pertains to a method for overexpressing target genes and/or reprogramming cells, the method comprising: (a) obtaining transformed cells by introducing a vector into which a promoter and target genes have been insert...  
WO/2020/071665A3
The present invention relates to an exosome for extending telomeres of cells, a composition comprising same, and a preparation method therefor and, more particularly, to an exosome for extending telomeres of cells, the exosome comprising...  
WO/2020/086701A1
Compositions and methods for reducing nucleotide oxidation during electroporation, specifically the use of free radical scavengers to reduce electroporation-induced oxidation, are described. Compositions and methods for enhancing transfe...  
WO/2020/080920A2
The present invention pertains to a method for overexpressing target genes and/or reprogramming cells, the method comprising: (a) obtaining transformed cells by introducing a vector into which a promoter and target genes have been insert...  
WO/2012/145019A8
Provided are methods of using compositions that include sets of magnetic particles, members of each set being conjugated to an antibody specific for a pathogen, and magnets to isolate a pathogen from a body fluid sample.  
WO/2020/071663A1
Disclosed is a method for producing exosomes having effects of skin regeneration and wound healing, comprising the steps of: providing ultrasonic stimulation directly or indirectly to cells; culturing a mixture of the cells and a medium ...  
WO/2020/071652A1
Disclosed are a method for extending the telomeres of cells and cells having telomeres extended by physical stimuli, the method comprising the steps of: providing direct or indirect physical stimuli for cells; and incubating a mixture of...  
WO/2020/071665A2
The present invention relates to an exosome for extending telomeres of cells, a composition comprising same, and a preparation method therefor and, more particularly, to an exosome for extending telomeres of cells, the exosome comprising...  
WO/2020/071662A1
Disclosed is a method for preparation of exosomes having a hair regeneration effect, the method comprising the steps of: providing direct or indirect ultrasonic stimuli for cells; incubating a mixture of the cells and a medium for a pred...  
WO/2020/070288A1
The inventors has developed a recombinant molecular system, named OptoFab, allowing the accurate control of the agonistic properties of an antibody-derived Fab fragment in time and in space using specific wavelengths of light. It consist...  
WO/2020/030037A1
Provided is the use of a nanosecond pulsed electric field in improving cell stemness. Specifically, applying a nanosecond pulsed electric field to cells, especially stem cells, can effectively increase the expression level of stemness ge...  
WO/2020/022382A1
A cell stimulation method that controls cell proliferation by stimulating cells without damaging the cells, by applying an AC electric field to the cells placed in an environment in which proliferation is possible.  

Matches 1 - 50 out of 1,961