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WO/2024/150101A1 |
An in-vitro traumatic brain injury induction device 1 having an elongated hollow tubular part 10 for passage of a weight 30 and at least one detachable head part 20 for attachment to an end of the body part, the head part having a wider ...
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WO/2024/150821A1 |
A molecule introduction device (1) comprises: a first electrode (10); a second electrode (20) that is spaced apart from the first electrode (10) and that is positioned in the direction in which a leading end (10a) of the first electrode ...
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WO/2024/077257A9 |
Systems and methods for electroporating a biological cell are disclosed. The system includes a microfluidic channel adapted to receive a flow of a plurality of biological cells in a buffer solution. The microfluidic channel comprises a d...
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WO/2024/143713A1 |
The present invention relates to a mutant strain of Corynebacterium, a method for producing the strain, and a method for producing L-alanine using the strain, the mutant strain having improved L-alanine productivity due to radiation-indu...
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WO/2024/136461A1 |
The present invention relates to a method for proliferating, differentiating, or promoting stem cells into osteogenic cells by using a planar heating element device made of a carbon fiber sheet. More specifically, when a planar heating e...
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WO/2024/136283A1 |
The present invention relates to a yeast mutant strain producing a high concentration of heme, and a method for high production of heme, using same. More specifically, provided are: a Saccharomyces yeast mutant strain which is prepared b...
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WO/2024/050514A9 |
A device, method, and kit are disclosed for use in detecting a target analyte in a sample. The device includes a region having a first zone, into which the sample can be delivered, and a second zone in fluid communication with the first ...
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WO/2024/122945A1 |
The present invention relates to a gene expression method for cancer cells, being capable of controlling demethylation of cancer cells without damage to DNA. The gene expression control method for cancer cells, according to the present i...
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WO/2024/118961A1 |
Disclosed are methods and systems for inducing a change in a polarization state of one or more macrophages. The method includes introducing one or more nanostructures into a microenvironment of one or more macrophages. The method further...
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WO/2024/119096A1 |
Provided herein are methods and systems for co-differentiating differentiatable cells in a population of differentiatable cells into two or more different cell lineages. In some embodiments, the methods and systems use light- or chemical...
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WO/2024/110594A1 |
The present invention generally relates to a method for enhancing the production of extracellular vesicles (EVs) from non-mammalian cells, the method comprising: (a) subjecting the cells to an acoustic and/or electromagnetic stimulation;...
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WO/2024/108566A1 |
Provided is an ultrasonic transducer for in-vivo transfection. The ultrasonic transducer is prepared by the following method: spin-coating a photoresist on the upper surface of a piezoelectric matrix to form a photoresist layer; covering...
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WO/2024/103125A1 |
Provided are methods and associated apparatus for increasing calcium mobilisation in a cell. Calcium mobilisation is through exposing the cells to acoustic wave energy such as through surface acoustic waves (SAW) and surface reflected bu...
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WO/2024/092300A1 |
The present disclosure relates to methods for differentiating mesenchymal stem cells (MSCs) towards an osteogenic lineage using daily short exposure to acoustic wave energy at a frequency greater than 1MHz. Methods disclosed herein can b...
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WO/2024/092321A1 |
The present disclosure relates to methods for modifying endothelial barrier function and cellular organisation through exposure to acoustic wave energy. In vitro models of endothelial barrier function and cellular organisation and method...
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WO/2024/066115A1 |
Disclosed are a method for enhancing the anti-tumor function of a T lymphocyte and use. The method comprises the step of culturing a T lymphocyte under a physical electrical stimulation condition, wherein the T lymphocyte comprises an in...
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WO/2024/054842A1 |
An apparatus and methods for electroporation of cells are disclosed. The apparatus comprises a memory storing instructions, a high voltage module to apply a voltage to cells, a low voltage module including a user interface, a system boar...
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WO/2024/040805A1 |
Provided are a nano material for generating ATP and NADPH under red light excitation and a method for preparing the nano material. By means of extracting and nanosizing a plant-derived thylakoid, a nano thylakoid is obtained to generate ...
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WO/2024/041201A1 |
Provided are a flow electroporation apparatus and a control method therefor. The control method comprises: starting a first electrode assembly at a first moment, forming an electric field in an electroporation chamber of the first electr...
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WO/2024/041200A1 |
Disclosed is a flow electroporation assembly, comprising a main liquid inlet, a main liquid outlet, a connecting pipeline, and at least two groups of electrode assemblies. Each group of electrode assemblies comprises two planar electrode...
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WO/2024/035147A1 |
The present invention relates to: an Lgr4 gene promoter or a fragment thereof regulated by electromagnetic waves; a vector comprising same; a composition for regulating gene expression by electromagnetic waves, the composition comprising...
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WO/2024/028532A1 |
The present invention relates to a thermoelectric device for measuring stress in photosynthetic organisms (11), stress which is caused by high and/or low temperatures, ultraviolet (UV) radiation and/or high photosynthetically active radi...
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WO/2024/028150A1 |
The present invention relates to a device (1) and its use for receiving a single-use container (44), comprising a receiving container (10) having an interior wall (16) that delimits a container interior of the receiving container (10) fo...
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WO/2024/025586A1 |
A feedback system (10) and method (30) that identifies characteristics (23, 25) of one or more cells (56) being grown on a metasurface (62) and utilizes the characteristics to initiate (35) and adjust (40) a field applied to the metasurf...
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WO/2024/020424A1 |
A bioengineered human tissue platform that allows quantitative studies of the effects of radiation, and cryoinjury on engineered cardiac tissue and engineered bone marrow.
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WO/2024/011248A1 |
Compositions and articles comprising scleroglucan that can be used for culturing and enumerating microorganisms even after exposure to sterilizing doses of radiation. The compositions also include one or more water swellable polymers oth...
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WO/2023/248085A1 |
Systems and methods are disclosed for inducing apoptosis and treating or reducing the occurrence of at least one condition, disease, disorder, or infection in a subject. The systems and methods rely on the application of an alternating e...
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WO/2023/240336A1 |
Systems and methods for growing cells or cell sheets are described. The method may use biocompatible or food-safe materials. The method may allow for cell alignment, optionally in selected patterns, which may be produced by casting a mem...
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WO/2023/239061A1 |
The present invention relates to a method for recovering metals from a waste battery by using a magnetic field-applied biological leaching process. According to the method of the present invention, by applying a magnetic field to the bio...
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WO/2023/227085A1 |
The invention relates to a cancer-specific T cell preparation method based on peripheral blood or peripheral immune organs for preventing or treating cancer. The preparation method specifically comprises: first, separating to obtain peri...
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WO/2023/221853A1 |
Disclosed in the present invention are a method for constructing a senescent cell and a method for evaluating the anti-senescence efficacy. The method for constructing the senescent cell comprises: performing seeding culture and subcultu...
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WO/2023/216227A1 |
Provided are a method for preparing a microbial microcapsule and a method for synthesizing a microbial flora (particularly a cross-species microbial flora). According to the principle that chitosan and sodium tripolyphosphate are subject...
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WO/2023/202608A1 |
The present application relates to the technical field of biology, in particular to a beauveria bassiana strain with high ultraviolet radiation resistance as well as a directional mutagenesis method therefor and use thereof. The beauveri...
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WO/2023/191559A1 |
The present invention relates to a method for mass proliferation of activated natural killer cells, and a use thereof. More specifically, provided is a method for inducing, differentiating, and mass-proliferating activated natural killer...
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WO/2023/152026A1 |
Process of making a mycelium based material in a mould. Electrical stimulation is used to control growth of the mycelium, in particular to stimulate mycelium growth during colonization of the substrate and/or to inhibit further growth in...
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WO/2023/142201A1 |
A method for the industrial production of a vaccine against Pseudomonas aeruginosa. By using a series of standardized, programmed and digital settings, it is ensured that a vaccine with stable quality containing whole Pseudomonas aerugin...
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WO/2023/147487A1 |
The present disclosure relates generally to high-frequency ultrasonicator devices, and more specifically to high-frequency ultrasonicator devices for disrupting or lysing cells, and methods for using those devices.
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WO/2023/141544A1 |
A method and system is provided for increasing lipids, biomass, and metabolite yields of a microalgae culture of cells and other organisms with conserved metabolic pathways compared to an untreated culture or organism when maintained und...
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WO/2023/126880A1 |
A method for morphologically altering and inhibiting the bacterial and viral functions is carried out by generating a magnetic field controlled by an operating signal ( C ) at a frequency comprised between 30 kHz and 300 kHz or comprisin...
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WO/2023/110063A1 |
The present invention relates an apparatus (1) and its use for in-vitro influencing biological cellular material by applying electric and/or electromagnetic emissions to the biological cellular material The apparatus (1) comprises a carr...
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WO/2023/108230A1 |
An apparatus for use in promoting motility of flagellar cells, comprising an acoustic energy emission module configured to generate ultrasound energy, the module being configured to generate ultrasound waves within a frequency range of a...
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WO/2023/114011A1 |
The present invention includes non-invasive methods of treating aging using low frequency structured and modulated ultrasound. The ultrasound irradiation causes mechanical stretching of cells even within the body of an organism which in ...
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WO/2023/100712A1 |
This light irradiation apparatus comprises an irradiation unit capable of irradiating an irradiation target with irradiation light having a radiation illuminance of 5 mW/cm2 or more in the wavelength range of 380 nm to 420 nm inclusive t...
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WO/2023/101369A1 |
The present invention relates to an islet-like organoid in which insulin secretion can be optically regulated by differentiating, into pancreatic islets, human pluripotent stem cells (monSTIM1-hPSC) obtained by knocking-in monSTIM1, whic...
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WO/2023/094503A1 |
The invention is directed to a process to convert carbon dioxide to methane by contacting an aqueous solution comprising dissolved carbon dioxide with an electron charged packed bed comprising of a carrier and a biofilm of microorganisms...
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WO/2023/085710A1 |
The present invention relates to a method for increasing the production of extracellular vesicles in a strain of the genus Lactobacillus, the method comprising a step for irradiating the strain with a red LED. According to the present in...
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WO/2023/079905A1 |
Provided is a cell peeling device that can efficiently peel cells that have uneven adhesion due to cell culturing conditions, peeling same in a non-contact manner from a culture container. This cell peeling device (10) peels cells (1) fr...
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WO/2023/065019A1 |
A bioreaction system and related methods are disclosed. The system comprises a sonic array comprising two or more transducers, the sonic array being configured to selectively emit sonication, each of the two or more transducers being con...
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WO/2023/055072A1 |
A device for forming a chondroprogenitor cell aggregate according to the present embodiment comprises: a plurality of wells in each of which a micromass is disposed; an electrical stimulation unit which provides electrical stimulation to...
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WO/2023/046709A1 |
The present invention relates to inactivated stem cells, which can be stored for several days in a refrigerator (above 0°C, preferably in the range 0.1-10°C) and still maintain their cellular and phenotypic integrity as well as therape...
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