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WO/1986/004353A1 |
Process for the intrasequential cofactor regeneration in enzymatic synthesis with one or a plurality of steps. In this process, a substrate is reduced by enzymes in a same reaction system (with one or a plurality of steps), and the reduc...
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WO/1986/003773A1 |
A process for increasing the solubility of gases in an aqueous medium. To the aqueous medium a silicone emulsion is added which comprises an aqueous emulsion of a copolymer of a silicone and a hydrophilic compound, optionally a mixture w...
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WO/1986/003774A1 |
Sporangiospores or germlings of fungi of the class Zygomycetes, in particular of the genus Mucor, are transformed with a recombinant expression vector by a method involving treatment of the germinating sporangiospores with a lytic enzyme...
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WO/1986/003205A1 |
An antibiotic, TAN-588, produced by bacteria belonging to genus Empedobacter or Risobacter, p-nitrobenzyl- or benzhydryl ester derivatives thereof, N-deacetyl derivatives thereof, and salts thereof have an anti-bacterial effect on Gram-p...
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WO/1986/002837A1 |
The adhesion of non-pathogenic bacteria to the stomach and intestines of humans and animals is increased by the administration of the bacteria in the presence of a protein, designated adhesive promoting protein, which can be produced by ...
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WO/1986/002094A1 |
Methods for selecting and isolating microorganism from nature that are capable of degrading lignin, processes for cloning a gene segment from such an organism, and methods of using the enzyme product of the gene segment to provide valuab...
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WO/1986/001407A1 |
A monoclonal antibody which exhibits specificity for a complex comprising a chelating agent and a first metallic ion. The antibody has an association constant (KA) for the complex of at least about ten times greater than the KA of the an...
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WO/1986/001225A1 |
A process for treating live cells for increasing their ability of fixing CO2 by introducing carbonic anhydrase (E.C. 4.2.1.1) activity into cytosol and/or cytomembrane of the cells.
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WO/1986/000339A1 |
In a process for recovering a polypeptide, such as an insulin-like material or hGH, from a fermentation broth, the fermentation broth is passed through a bed of a chromatographic material containing hydrophobic groups, such as phenyl sep...
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WO/1986/000019A1 |
Vaccine intended to protect against diseases caused by a micro-organisms having a membrane as the most external envelope, particularly, a mycoplasm, characterized in that it contains, as active principle, plasmic membranes of the micro-o...
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WO/1985/005561A1 |
Continuous chemical and biological reactions may be carried out in a liquid fluidized reactor (1). Improved mixing and mass transport between gas/liquid/solid phases is provided by fluidizing large particles (2) with a liquid in a dense ...
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WO/1985/005109A1 |
Antibiotic TAN-588 produced by a bacterium belonging to the genus Empedobacter, and its salt have an antibacterial effect on gram-positive and gram-negative bacteria, and are used for treating bacteria-induced diseases of mammals, poultr...
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WO/1985/004883A1 |
Bacteriostatic substance GIF-2 is obtained from, for example, a culture liquor of Bacillus cereus SW, and has the presumed formula (I), wherein one of the three X's has an amido bond, and R represents the beta-amino acid residue of formu...
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WO/1985/004408A1 |
Antibiotic TAN-588 produced by bacteria belonging to genus Empedobacter, and its salts have an anti-bacterial effect on gram-positive and negative bacteria, and can be used for treating bacteria-induced diseases of mammals and poultry.
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WO/1985/002414A1 |
A method for increasing the rate of chemical reactions involving the conversion of at least one reactant to at least one product involves contacting the reactant with an appropriate monoclonal antibody under conditions permitting the for...
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WO/1985/002197A1 |
A method compound and composition for degrading crude petroleum and petroleum products in any environment. Crude petroleum or petroleum products are contacted with an effective amount of a strain of the fungus Actinomucor elegans (Ediam)...
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WO/1985/002196A1 |
A method, compound and composition for degrading crude petroleum and petroleum products in any environment. Crude petroleum or petroleum products are contacted with an effective amount of a novel fungus, Geotrichum marinum Thirumalachar ...
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WO/1985/001743A1 |
An aerobic microbiological method in which a microorganism (2) is immobilized in a fluid-permeable fiber matrix (1) and supplied with a substrate solution (6) and an oxygen-containing gas (10) which are supplied to and leave the matrix a...
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WO/1985/000977A1 |
The vaccine or antigen against paludism is characterized in that it comprises, in an appropriate vehicle, at least some of the exo-antigens obtained from the supernatants from the culture of Plasmodium falciparum cultivated on human eryt...
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WO/1985/000607A1 |
Antibiotic TAN-542 produced by microorganisms belonging to genus Flexibacter and its salts possess an antibacterial effect against Gram-positive and Gram-negative bacteria, and can be used as agents for treating bacterial infection of ma...
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WO/1984/003104A1 |
T-cell DNA synthesis-repressing substance comprising a low-molecular peptide having the following physical and chemical properties: (a) elemental analysis: C, H, O, N, and S are present; (b) molecular weight: about 1,000 Dalton; (c) pH s...
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WO/1984/002652A1 |
By the combination of cryocrushing, molecular crushing, turbosettling and ultra-filtration, an extremely beneficial liquid product is physically obtained. Said product is sterile. Treatment of algae and complete plants, particulalry arti...
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WO/1984/000777A1 |
A method for increasing the production of a secondary metabolite, such as an antibiotic, in a fermentation which comprises periodically adding to the culture medium during the idiophase of the fermentation those nutrients essential for p...
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WO/1984/000383A1 |
A biochemical enzymatic reaction involving an oxidizing enzyme which converts a substrate to an oxidized product with NAD+ or NADP+ as coenzyme with a recycling system for returning the NADH or NADPH produced to the oxidized state by the...
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WO/1983/002776A1 |
This antibiotic substance, yielded by a novel strain belonging to Streptomyces hygroscopicus, exhibits antibacterial action against various bacteria and is useful as an effective ingredient in an antibacterial agent.
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WO/1983/000930A1 |
Mediator substances exhibiting inhibitory effect upon anabolic enzyme activity in mammals, are prepared by a method comprising gathering a sample of macrophage cells from a mammal, incubating a portion of the macrophage cells with a stim...
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WO/1983/000630A1 |
A process for recovering silver and photosensitive material base in a reusable form from a photosensitive material such as film or photographic paper having on its surface a gelatin membrane containing fine silver crystals by decomposing...
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WO/1983/000444A1 |
A filtration method and related apparatus for extracting cell-produced antiviral substances (especially human leukocyte interferon) from a production broth using a single module or dual module filtration cell means wherein the first filt...
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WO/1983/000148A1 |
Antibacterial effect-enhancing substance F2 yielded by pseudomonad and its salt have the effect of enhancing antibacterial effect of beta-lactam antibiotics, and can be used for treating bacterial diseases of mammals, fowl, etc.
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WO/1982/004262A1 |
Production of two products which are distinct species of anti-malignin antibody, and the production of three artificially produced species of cell each of which has the distinguishing characteristic of manufacturing either one or both sp...
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WO/1982/003873A1 |
Organic compounds susceptible to hydrolysis are prepared by reaction in a water-immiscible organic liquid in contact with an enzyme activated with water to catalyse the reaction and desiccant means to lower the water activity of the disp...
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WO/1982/003729A1 |
Electrodes for the electrochemical regeneration of the co-enzymes NADH, NADPH or analogs thereof. The electrode surface has been modified by adsorbing thereto a condensed aromatic ring system comprising at least three, preferably four or...
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WO/1982/003089A1 |
A monoclonal antibody having specificity for an antigenic determinant of a B-type blood cell. The monoclonal anti-B, produced by a hybridoma cell (the preparation of which is described), affords a defined, specific and cheap blood groupi...
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WO/1982/002561A1 |
The activity of a microbiologically active material is measured by suspending the material in a liquid medium capable of forming a gel. The resultant suspension is formed into small liquid droplets, which droplets are caused to gel. The ...
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WO/1982/001721A1 |
Culture medium, extract, active mixture and compounds with antibiotic activity obtained by microbiological process by means of the microorganism DSM 1888.
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WO/1982/001707A1 |
Novel antibiotic 5057B and process for its preparation. Antibiotic 5057B itself is an acidic material, and its sodium salt has the following physical and chemical properties: (1) colorless, needle-like crystals; (2) melting point: 143 to...
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WO/1982/001563A1 |
Method for carrying out biological and chemical conversion processes which require the presence of one or more catalytically active substances, such as enzymes, microorganisms, cells, organelles, cell homogenates, and organic or inorgani...
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WO/1982/001010A1 |
A plant-derived cell aggregate, comprising a plurality of undifferentiated cells is disclosed, as is a plant granulate comprising a plurality of such aggregates. A process for the production of such an aggregate comprising establishing a...
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WO/1982/000587A1 |
The antibiotics S 41062/F-1, S 41062/F-6 and S 41062/F-7 are obtained from a new Cryptosporiopsis strain.
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WO1982000146A1 |
Antibiotic Y-16482(Alpha) and/or antibiotic Y-16482(Beta) obtained by culturing antibiotic Y-16482-producing bacteria belonging to genus Pseudomonas, process for their preparation, and medicinal composition containing the same. Antibioti...
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WO/1981/003666A1 |
Methods of producing glucosone which comprises enzymatically oxidizing glucose with glucose-2-oxidase in the presence of an enzyme which reduces hydrogen peroxide, said reducing enzyme being in immobilized form suspended in the reaction ...
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WO/1981/003664A1 |
Methods of producing glucosone which comprises enzymatically oxidizing glucose with glucose-2-oxidase in a first zone and separating the concomitantly produced hydrogen peroxide from said first zone through a semi-permeable membrane into...
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WO/1981/003663A1 |
Human hepatoma cell lines, useful for metabolic studies such as screening potential carcinogens and mutagens, for cultivation of viruses, and for preparation of vaccines, are obtained by culturing human hepatocarcinoma or hepatoblastoma ...
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WO/1981/002520A1 |
Compositions for therapeutic or diagnostic use in connection with bacterial infections containing as an active constituent the structural element, preferably in terminal position: (FORMULA) A process for the therapeutic treatment of mamm...
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WO/1981/002308A1 |
Process for converting organic material in a microbiological way under gas generation, the conversion being carried out in a reaction vessel by means of microorganisms which are grown on a movable bed of inorganic granular material and f...
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WO/1981/001714A1 |
Spherical shaped mycelial pellets suitable for use in the biocatalytic conversion of organic compounds are described which comprise a rigid spherical core surrounded by a porous webbed layer having structural integrity of a mycelial micr...
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WO/1981/001153A1 |
The invention relates to eucaryote cells, eucaryote protoplasts and eucaryote pluricellular living organisms having a certain ADN concentration, introduced by means of lipidic vesicles. Disclosed are a process for the preparation thereof...
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WO/1981/000962A1 |
Antibiotic polypeptide compound, or addition salt thereof, having a molecular weight no greater than 10000 and possessing bactericidal and bacteriolytic activities in respect of Gram-positive bacteria, the said compound comprising within...
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WO/1981/000723A1 |
A novel strain of Trichosporon Kashiwayama (FERM-P No. 4821), a cultivated product thereof, culture medium, cell-free medium, germfree filtrate, germfree supernatant, concentrate or dried product thereof, a process for preparing them, an...
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WO/1981/000575A1 |
Process for the microbial fermentation of an organic substrate as well as to a microbial catalyst used in the process. The catalyst being of the immobilized microorganism type is magnetically influenced, a property which is used in order...
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