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WO/2000/050388A1 |
A process for producing nitrosonium ions is described, in which a nitroxyl compound such as TEMPO is oxidised using an oxidising agent in the presence of a complex of a transition metal such as Mn, Fe, Cu, and a complexing agent such as ...
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WO/2000/047709A1 |
Subculturing apparatus (30) comprises a receptacle for supporting a growth medium (5) for culturing of a microorganism. The microorganism is entrained to grow in a predetermined direction, towards an end of the growth medium (50), where ...
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WO/2000/044389A2 |
The invention concerns a method for preparing membrane vesicles from a biological sample, characterised in that it comprises at least a step which consists in treating the sample by anion-exchange chromatography and/or gel permeation. Th...
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WO/2000/043532A1 |
The invention relates to a method for carrying out enzyme reactions, characterized in that the products formed during the enzymatic reaction are separated by chromatography simultaneously with the reaction.
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WO/2000/040712A1 |
The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; (b) expressing the geneti...
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WO/2000/033934A1 |
The present invention relates to a method of separating a first solute A and a second solute B using (simulated) moving bed chromatography. According to the present invention at least one of a) a feedstream; and b) a desorbent stream com...
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WO/2000/028947A2 |
The invention concerns the use of a substance specifically binding with the peripheral benzodiazepin receptor (PBR) for making a composition for preventing or treating skin stress. The invention also concerns compositions containing said...
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WO/2000/021978A2 |
The present invention features two novel members of laminin family, $i(i.e.), laminin 13 and laminin 14, the methods of making these molecules, and the methods of using these molecules in treating neural disorders, $i(e.g.), retinal diso...
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WO/2000/020618A2 |
The invention relates to a method for fragmenting fermentation residues formed during fermentation containing a substantial portion of inorganic substances, wherein fermentation residues are conditioned or subjected to conditioning, cult...
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WO/2000/017331A1 |
The present invention relates to isolated polypeptides having polypeptide having 2,6-$g(b)-D-fructan hydrolase activity and isolated nucleic acid sequences encoding the polypeptides. The invention also relates to nucleic acid constructs,...
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WO/2000/009761A1 |
Sulfur is removed from fossil fuels containing sulfur by incubation of the fuel with microbes isolated and purified from soil or water that selectively extract the sulfur without apparently utilizing the fuel as a carbon or energy source...
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WO/2000/003021A2 |
The present invention concerns a microbial cell comprising a first expressible enzyme activity, e.g., pyridine nucleotide transhydrogenase from $i(Azotobacter vinelandii) which, when expressed in said microbial cell, is controlling an in...
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WO/1999/067408A1 |
The present invention relates to a compound named Mumbaistatin which is obtainable by cultivation of the microorganism HIL-008003 (DSM 11641), and to its pharmaceutically acceptable salts and derivatives. Mumbaistatin is a glucose-6-phos...
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WO/1999/063102A1 |
The present invention provides new bioactive compounds WF19353 substances which have the inhibitory activity against gluconeogenesis, and a process for producing the same by fermentation of a WF19353 substances-producing strain belonging...
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WO/1999/061645A1 |
The present invention provides a new bioactive compound, WF00144 substance or its salt which has an inhibitory activity against gluconeogenesis, and a process for production of the same, which comprises culturing a WF00144 substance-prod...
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WO/1999/060150A1 |
The invention relates to a method for catalysing complex reactions of large molecules, more specifically, to enzyme-catalysed reactions during which undesirable consecutive or subsidiary reactions usually occur; using enzymes which are b...
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WO/1999/057302A1 |
A process for obtaining a protein hydrolyzate by enzymatically hydrolyzing a vegetable protein material containing saccharides by using a mold culture in a liquid reaction system, which comprises mixing the vegetable protein material wit...
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WO/1999/055896A1 |
The present invention relates to a novel glucose-6-phosphate translocase inhibitor L 970885, which is produced by an Actinomycete sp. (culture number HIL-000337) during fermentation, a process for its preparation, to chemical derivatives...
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WO/1999/055897A1 |
The invention relates to a method for oxidising substituted trimethylcyclohexenyl compounds in the presence of microorganisms of the actinomycetal order and to the use of microorganisms in oxidation reactions.
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WO/1999/055895A1 |
The present invention relates to a novel glucose-6-phosphate translocase inhibitor L 970871, which is produced by an Actinomycete sp. (culture number HIL-007997) during fermentation, a process for its preparation, to chemical derivatives...
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WO/1999/055877A1 |
The invention relates to a process for microbially preparing substances from aromatic metabolism, in particular aromatic amino acids. In addition, the invention relates to gene structures and transformed cells. According to the invention...
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WO/1999/053015A1 |
The invention relates to a process for isolating a desired water-soluble product from a fermentation broth wherein the broth is circulated along a ceramic membrane, and wherein a trans-membrane pressure of at least 1.5 bar is applied, wh...
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WO/1999/050388A1 |
The present invention relates to $i(Streptomyces) sp. producing tautomycetin which possesses an immunosuppressive or antibacterial activities, a process for preparing tautomycetin from the said microorganism, and an immunosuppressant or ...
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WO/1999/043826A1 |
The present invention relates to an isolated nucleic acid molecule which encodes one or more of the enzymes which catalyze one or more steps in the desulfurization of thiophene, or a homologue or active fragment thereof. The invention al...
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WO/1999/034054A1 |
The present invention provides a process for removal of excess dye from newly manufactured printed or dyed fabric or yarn, comprising treatment with a rinse liquor comprising at least one enzyme selected from the group consisting of enzy...
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WO/1999/032604A1 |
The present invention provides an isolated linoleate isomerase and its nucleic acid and amino acid sequence. The present invention also provides a method for producing CLA from an oil using an immobilized bacterial cell or an isolated li...
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WO/1999/029885A1 |
The invention relates to the degradation of moulded bodies, flat materials, coatings, adhesive bonds or foams which consist of biodegradable polymers using pure cultures of micro-organisms and the enzymes produced by these micro-organism...
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WO/1999/025735A1 |
Disclosed herein is a chimeric protein comprising a pre-activated transcription factor and a strong transcription activation domain for regulating fungal gene expression, and reagents and methods for constructing and using said protein.
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WO/1999/025719A1 |
A physiologically active substance, sulphostin, having a potent dipeptidylpeptidase IV inhibitory activity and obtained by culturing a microorganism belonging to the genus Streptomyces and capable of producing the above substance to accu...
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WO/1999/024597A1 |
The invention relates to a method for producing L(-)-carnitine. The aim of the invention is to depict a method which permits the synthesis of L(-)-carnitine from crotonobetaine, crotonobetaine salts or derivatives in an ecologically adva...
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WO/1999/023996A2 |
Methods and compositions are disclosed which comprise red rice fermentation products, that can be used as natural dietary supplements and/or medicaments for the treatment or prevention of hyperlipidermia and associated disorders and symp...
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WO/1999/016893A2 |
The invention relates to an enzymatic oxidation process comprising of bringing together an oxidative enzyme, a hydrogen acceptor and a hydrogen donor in a reaction mixture and causing an oxidative reaction to proceed in the reaction mixt...
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WO/1999/011751A2 |
The object of the present invention is to provide a fermentation product excellent in flavoring quality by a method in which the fermentation time can be reduced and the long-term operation is feasible in producing the fermentation produ...
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WO/1999/009819A1 |
A novel strain of $i(Bacillus subtilis) is provided that produces a metabolite that exhibits pesticidal activity. Also included in the invention is a solvent extractable and water soluble, large molecular weight ($m(g)10,000 daltons) met...
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WO/1999/009974A1 |
4-Cyano-4-deformylsordarin derivatives are antifungal agents useful in the treatment and/or prevention of human and animal fungal infections, as well as in the control of phytopathogenic fungi in crops.
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WO/1999/010477A1 |
A novel pesticidal metabolite-producing $i(Bacillus pumilus) strain is provided. In addition, a supernatant of the novel strain with pesticidal activity is provided. A solvent-extractable, small molecular weight (< 10,000 daltons) metabo...
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WO/1999/010521A1 |
Materials and methods for selectively adsorbing proteins are disclosed. The invention describes controlled pore glass treated with a cationic portion electrostatically attracted to the porous outer surface of the glass. The constitutents...
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WO/1998/058072A1 |
The invention provides a process for the production of (meth)acrylic acid or salt thereof comprising providing (meth)acrylonitrile starting material and contacting it in an aqueous reaction mixture with an enzyme catalyst which comprises...
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WO/1998/056904A1 |
The invention relates to the formation of novel $i(in vivo) combinatorial enzyme complexes for use in screening candidate drug agents for bioactivity.
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WO/1998/055822A2 |
Technology for $i(in situ) remediation of undetonated explosive device. An explosive apparatus (16) includes an explosive material (30) in close proximity with a quantity of microorganisms capable of metabolizing explosive material (30)....
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WO/1998/053047A1 |
The present invention concerns a novel bacterial autoinducer, methods of its manufacture, isolation and purification, uses of autoinducer isolated and purified using same, and the uses of the autoinducer.
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WO/1998/051811A1 |
A process for the manufacture of oxygenated organic compounds by employing an oxidase to generate H�2?O�2? is disclosed. The generated H�2?O�2? is used to oxidize an oxidizable organic substrate in the presence of a metal-contain...
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WO/1998/048276A1 |
A novel predator bacterium $i(Burkholderia casidae) is disclosed. The invention is directed to the isolation and use of $i(Burkholderia casidae) to control microbial diseases of plants. The genetic, biochemical and physiological characte...
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WO/1998/037179A2 |
The present invention describes the use of chemically defined media for the fermentative production of valuable compounds on an industrial scale. Microbial strains which are suitable for fermentation on an industrial scale using a chemic...
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WO/1998/037176A1 |
The present invention relates to a method for increasing the growth rate and concentration of $i(in vitro) cultivated plant cells by re-induction and stimulation of the growth of plant cells, which comprises the steps of: a) growing plan...
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WO/1998/036086A1 |
The invention relates to the complete degradation of shaped bodies, textile fabrics, coatings, bondings or foams made of biologically degradable polymers using enzymes. The invention particularly relates to enzymatic degradation of polye...
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WO/1998/035768A1 |
A process for remediation of contaminated solid materials comprising polynuclear aromatic hydrocarbon contaminated solid materials, polychlorinated hydrocarbon contaminated materials, and mixtures thereof by sequential biological/chemica...
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WO/1998/035017A1 |
The present invention relates to antifungal biocontrol agents which enhance plant growth and reduce plant diseases by suppressing fungal pathogens, and the manufacturing and application methods thereof. The antifungal biocontrol agents o...
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WO/1998/031824A1 |
A compound produced by a fungal species, preferably an $i(Epicoccum) species, suitable for use as a fluorescent marker for a biomolecule, capable of binding to a biomolecule, and which emits fluorescence in red wavelengths after excitati...
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WO/1998/028043A2 |
The invention relates to the new bacterial strain $i(Corynebacterium sp. K2-17) and a method for the microbial decontamination of materials which are contaminated with compounds from phenoxyalcanoic acid-herbicide production, like for ex...
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