| Document |
Document Title |
|
WO/2012/077994A2 |
The present invention relates to microbes with an improved ability to produce ornithine and a method for producing ornithine using the microbes by: blocking a biosynthetic pathway from ornithine to arginine; increasing the amount of glut...
|
|
WO/2012/077744A1 |
Disclosed is a novel method for producing cadaverine, said method being able to produce cadaverine at a higher yield and a greater efficiency than production methods by means of conventional fermentation methods. The method for producing...
|
|
WO/2012/071768A1 |
Method for preparing high quality Euphausia superba oil with phosphatidylserine enriched of polyunsaturated double bond fatty acyl group, which includes the following steps: 1) solvent extracting Euphausia superba oil to obtain phosphati...
|
|
WO/2012/063826A1 |
The present invention provides a lactic acid bacterium which has high proteolysis activity and thus has excellent peptide production ability and/or amino acid production ability. The present invention also provides fermented milk which c...
|
|
WO/2012/058919A1 |
A method for enhancing the rate of acid production of genetically engineered bacteria producing L-phenylalanine is provided, comprising: amplifying the whole phosphoenolpyruvate carboxykinase (pckA) gene by PCR and inserting the amplifie...
|
|
WO/2012/055798A1 |
The present invention is related to a microorganism for the production of methionine, wherein said microorganism is modified to enhance the transhydrogenase activity of PntAB. In a preferred aspect of the invention, the activity of the t...
|
|
WO/2012/057598A1 |
The present invention relates to an HPLC method for quantifying free amino acids in the shrimp-head hydrolysate obtained by means of lactic fermentation. For the purpose of analysis thereof, the samples were derivatized with 9-fluorenylm...
|
|
WO/2012/057597A1 |
The present invention relates to a method for obtaining free amino acids from protein hydrolysates derived from shrimp by-products. The method was used to quantify the amino acids present in the liquor obtained as final product in lactic...
|
|
WO/2012/053794A2 |
The present invention relates to a method for production of cysteine or its derivatives using O-phosphoserine as an intermediate and recombinant microorganism for use in production of O-phosphoserine.
|
|
WO/2012/053777A2 |
Disclosed is an O-phosphoserine sulfhydrylase (OPSS) mutant which has a Mycobacterium smegmatis-derived amino acid sequence corresponding to that of SEQ ID NO: 1 which is devoid of three to seven C-terminal amino acid residues. Also, a n...
|
|
WO/2011/129820A9 |
The present invention generally relates to processes for the enzymatic production of a phosphinothricin product or precursor thereof from a nitrile-containing substrate.
|
|
WO/2012/043622A1 |
Provided is a process for producing an optically active amino compound, which is a compound useful as an intermediate for a medicine, an agrochemical or the like, from a ketone compound with high efficiency. A polypeptide which has high ...
|
|
WO/2012/044120A2 |
The present invention relates to a method for preparing 2-pyrrolidone using biomass, comprising: a step (a) of culturing a microorganism which contains glutamate decarboxylase as a whole-cell catalyst in a culture medium containing gluta...
|
|
WO/2012/039407A1 |
[Problem] To provide a method for efficiently producing an amide compound without reducing the activity of a microbial catalyst, and to provide a device for producing an amide compound that can be advantageously used in this method. [Sol...
|
|
WO/2012/036301A1 |
A process for producing a vinylglycine derivative, comprising a reaction with a vinyl glyoxylic acid derivative and a transformant harboring an amino acid dehydrogenase gene.
|
|
WO/2012/036151A1 |
Provided are sulfur amino acid-producing bacteria, and a method for producing sulfur amino acid compounds, etc, using said bacteria, using new techniques developed to improve sulfur amino acid production by bacteria. Bacteria belonging t...
|
|
WO/2012/036302A1 |
The present invention provides a process for producing a vinylglycine derivative represented by the formula (2): wherein R1 represents hydrogen, an alkyl group having 1 to 8 carbon atoms, or an aryl group having 6 to 20 carbon atoms; or ...
|
|
WO/2012/031910A2 |
The invention relates to a method for preparing alpha-ketopimelic acid, comprising converting alpha-ketoglutaric acid into alpha-ketoadipic acid and converting alpha-ketoadipic acid into alpha-ketopimelic acid, wherein at least one of th...
|
|
WO/2012/034043A1 |
This invention pertains to methods for producing homogeneous recombinant proteins that contain polymer initiators at defined sites. The unnatural amino acid, 4-(2'-bromoisobutyramido)phenylalanine of formula 1, was designed and synthesiz...
|
|
WO/2012/031911A2 |
The invention is directed to a method for preparing 6-aminocaproic acid, comprising decarboxylating alpha-aminopimelic acid, using at least one biocatalyst comprising an enzyme having alpha-aminopimelic acid decarboxylase activity. The i...
|
|
WO/2012/026581A1 |
A technique in which a sugar solution that can be used as a carbon source for culturing a microorganism is efficiently manufactured from a biomass feedstock and the obtained sugar solution is used to manufacture a target substance via fe...
|
|
WO/2012/024104A2 |
The disclosure provides transaminase polypeptides capable of converting the substrate, 2-(3,4-dimethoxyphenethoxy)cyclohexanone to the trans diastereomer product (1R,2R)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine in at least a 2:1 diaste...
|
|
WO/2012/018226A2 |
The present invention relates to a mutant microorganism having a high production of cadaverine, a preparation method of cadaverine using the same, and more specifically, to a mutant microorganism having a high production of cadaverine in...
|
|
WO/2012/013765A1 |
The invention relates to an enzymatic acylation method including at least the following steps of: contacting at least one compound having at least one function selected from among the amine, alcohol, or thiol functions, at least one micr...
|
|
WO/2012/014228A1 |
A method to bypass allosteric domain activity of an enzyme so as to alter the feedback/ feed-forward inhibition/ activation, comprises of (i) a method of increasing the downstream metabolic product such in fermentation or for genetically...
|
|
WO/2012/011596A1 |
The present invention provides a method for producing L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus Escherichia or Pantoea, which has been modified to enhance the express...
|
|
WO/2012/012640A1 |
A pharmaceutical composition and method for providing a reduction in side effects for human patients in need of therapy comprising the administration of a pharmaceutical composition comprising acetylcysteine is disclosed.
|
|
WO/2012/011214A1 |
As a means for effectively utilizing a fermentation residue (cake), the present invention provides a method which comprises removing impurities from an alcoholic extract of a cake using a nonsolvent for free ceramides, such as hexane or ...
|
|
WO/2012/011595A1 |
The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression...
|
|
WO/2012/008810A2 |
Disclosed is an L-lysine-producing microorganism having gluconate kinase activity weakened in comparison to the endogenous activity thereof, and methods provided for preparing the microorganism and for producing L-lysine using the same.
|
|
WO/2012/008809A2 |
The present invention relates to an L-ornithine-producing microorganism, in which the gluconate kinase (GntK) activity is weakened relative to an intrinsic activity thereof, and to a method for producing L-ornithine from the L-ornithine-...
|
|
WO/2012/007548A1 |
The present invention relates to a method for the enzymatic synthesis of enantiomerically enriched (R)-amines of general formula [1][c],from the corresponding ketones of general formula [1][a], by using novel transaminases. These novel t...
|
|
WO/2012/005372A1 |
The present invention provides a novel process for producing a sulfur-containing α-amino acid compounds such as methionine. A process for producing a sulfur-containing α-amino acid compound (Compound 2) comprising a step of reacting a ...
|
|
WO/2012/002575A1 |
The present invention provides a novel process for producing a sulfur-containing α-amino acid compound such as methionine. A process for producing a sulfur-containing α-amino acid compound represented by the formula (2): wherein R1 rep...
|
|
WO/2012/002486A1 |
Provided is a method for efficiently producing an L-amino acid from ethanol as the starting material using a bacterium belonging to the family Enterobacteriaceae, and also provided is a bacterium used in this method. A bacterium modified...
|
|
WO/2011/159853A1 |
The present invention is related to recombinant host cells comprising: (i) at least one deletion, mutation, and/or substitution in an endogenous gene encoding a polypeptide that converts pyruvate to acetaldehyde, acetyl-phosphate or acet...
|
|
WO/2011/159971A1 |
The present invention comprises methods and pharmaceutical compositions for intranasal delivery of effective amounts of DFO directly to the CNS, in particular the brain treatments that inhibit GSK3b in patients with psychiatric disorders...
|
|
WO/2011/158970A1 |
The present invention provides a novel process for producing a sulfur-containing α-amino acid compound such as methionine. A process for producing a sulfur-containing α-amino acid compound represented by the formula (2): wherein R1 rep...
|
|
WO/2011/158194A1 |
The present invention is concerned with a process of preparing (R)-lacosamide. The process comprises providing an (R,S)-lacosamide precursor and contacting the same with at least an enzyme in the presence of a solvent. The enzyme either ...
|
|
WO/2011/158975A1 |
The present invention is directed to a method utilizing a recombinant microorganism for the production of aspartate derived amino acids and precursors therof, in particular for the production of L-lysine. Furthermore, the present inventi...
|
|
WO/2011/152565A1 |
The present invention provides a method for producing L-amino acids, such as L-arginine, L-citrulline, and L-lysine, using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus Escherichia or Panto...
|
|
WO/2011/152568A1 |
The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, in which expression of the gene encoding a lysi...
|
|
WO/2011/130608A9 |
Methods and compositions for enhancing female sexual arousal and treating female sexual dysfunction utilize L-arginine or equivalents and/or derivatives thereof, and an agent that enhances the activity of the L-arginine or equivalent the...
|
|
WO/2011/152540A1 |
The present invention relates to a process for producing methionine, comprising a first step of reacting 2-amino-3-buten-1-ol with methanethiol, and a second step of oxidizing 2-amino-4-methylthio-1-butanol obtained in the first step. Th...
|
|
WO/2011/148867A1 |
Disclosed is a method that uses a reaction vessel having a plug-flow region to hydrate a nitrile compound at a high conversion rate, thereby continuously manufacturing a high-concentration aqueous solution of an amide compound. Said meth...
|
|
WO/2011/145525A1 |
Disclosed is a seasoning composition which is highly safe to the human body and has excellent sweetness and first taste. The seasoning composition can be used as an alternative to an animal protein hydrolysate without causing any problem...
|
|
WO/2011/145687A1 |
Provided is a method for preserving, in a stable state, an amide compound having an unsaturated bond, which is industrially very important but very easily undergoes polymerization and, therefore, is very hard to handle, without adding a ...
|
|
WO/2011/141175A1 |
The invention relates to a process for the recovery of betaine from a molasses, comprising: a conversion step, in which the molasses is subjected to the action of an enzyme having endo-inulinase activity and/or fructosyltransferase activ...
|
|
WO/2011/138966A1 |
Disclosed is a method for more efficiently producing acrylamide from acrylonitrile using the action of microbially derived nitrile hydratase. More specifically disclosed is a method for producing acrylamide from acrylonitrile using a bio...
|
|
WO/2011/138006A1 |
The present invention relates to a cell which has been modified recombinantly over its wild type and which comprises a gene sequence coding for an autofluorescent protein, the expression of the autofluorescent protein being dependent on ...
|
