Title:
【発明の名称】少なくとも三つのトランス遺伝子を発現する抗腫瘍性細胞組成物
Document Type and Number:
Japanese Patent JP2000507260
Kind Code:
A
Abstract:
A novel antitumour composition including a cell population capable of expressing at least three therapeutic genes, particularly immunostimulatory and/or cytotoxic genes, is disclosed. A packaging cell expressing interleukin-2 and a retroviral vector expressing the gamma-interferon and thymidine kinase genes of herpes simplex virus 1 (HSV-1), as well as the therapeutical use thereof for preventing and treating cancer, are also disclosed.
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Inventors:
Majid, Metari
Horst, homann
Eve, poit van
Horst, homann
Eve, poit van
Application Number:
JP53408697A
Publication Date:
June 13, 2000
Filing Date:
March 25, 1997
Export Citation:
Assignee:
TRANSGENE S.A.
International Classes:
C12N15/09; A61K31/00; A61K31/52; A61K31/522; A61K35/76; A61K38/00; A61K38/21; A61K38/46; A61K48/00; A61P35/00; C07K14/15; C07K14/53; C07K14/535; C07K14/54; C07K14/55; C07K14/555; C07K14/57; C12N5/10; C12N7/04; C12N15/867; (IPC1-7): A61K48/00; A61K31/522; A61K35/76; A61K38/00; A61K38/21; A61K38/46; A61P35/00; C07K14/15; C07K14/53; C07K14/535; C07K14/54; C07K14/555; C12N5/10; C12N15/09
Attorney, Agent or Firm:
Kazuo Sato (2 outside)