Title:
【発明の名称】細胞における局在性が改変された免疫ポリペプチドに基づく抗腫瘍組成物
Document Type and Number:
Japanese Patent JP2001510201
Kind Code:
A
Abstract:
Antitumoral compositions can comprise as therapeutic agent one or several immunogenic polypeptides, of which at least one is modified so as to have a cell location different from its native location. Compositions can be based on a recombinant vector expressing such an immunogenic polypeptide. A recombinant vector comprising at least the sequences coding for an immunogenic polypeptide originating from a precocious and/or tardive region of a papillomavirus having a modified location and a viral particle comprising said vector is also described. Finally, therapeutic uses of such a composition, such a recombinant vector and such a viral particle are described.
Inventors:
Marie-Paul, Kearney
Jean-Marc, Barur
Nadine, Bizarne
Jean-Marc, Barur
Nadine, Bizarne
Application Number:
JP2000503107A
Publication Date:
July 31, 2001
Filing Date:
July 17, 1998
Export Citation:
Assignee:
TRANSGENE S.A.
International Classes:
A61K39/12; A61P31/20; A61P35/00; A61P37/04; C07K14/025; C12N7/00; C12N15/09; A61K38/00; (IPC1-7): C07K14/025; A61K39/12; A61P31/20; A61P35/00; A61P37/04; C12N7/00; C12N15/09
Attorney, Agent or Firm:
Kazuo Sato (3 others)