Title:
【発明の名称】N,N,6-トリメチル-2-(4-メチルフェニル)-イミダゾ-[1,2-a]-ピリジン-3-アセトアミドおよびその塩の製造方法
Document Type and Number:
Japanese Patent JP2002522437
Kind Code:
A
Abstract:
It comprises reducing the hydroxy ester of formula (X) by reacting it in DMF and then with an iminium salt of formula (XIII) formed in situ with thionyl chloride and dimethylformamide, and subsequent reduction with an appropriate reducing agent to form the ester of formula (XII), which is then reacted with dimethylamine in a polyhydroxylated solvent medium at an appropriate temperature.
Inventors:
Rafael, Rabriola
Application Number:
JP2000563654A
Publication Date:
July 23, 2002
Filing Date:
August 04, 1999
Export Citation:
Assignee:
QUIMICA SINTETICA, S.A.
International Classes:
A61K31/415; A61K31/435; C07D471/04; (IPC1-7): C07D471/04
Attorney, Agent or Firm:
Kenji Yoshitake (4 others)