Title:
【発明の名称】二本鎖RNAレセプター(dsRNA-R)およびそれに関連する方法
Document Type and Number:
Japanese Patent JP2003514791
Kind Code:
A
Abstract:
The present invention is directed to nucleic acid molecules and polypeptides encoding a CpG receptor (CpG-R). The CpG-R contains a THD, interacts with the MyD88 adapter protein, and may bind to CpG oligonucleotides. The present invention is also directed to antibodies against CpG-R and to methods of modulating an immune response and to methods of identifying compounds which bind to and/or modulate CpG-R.
Inventors:
McKee Chan, Mary Lee
Application Number:
JP2001538520A
Publication Date:
April 22, 2003
Filing Date:
November 01, 2000
Export Citation:
Assignee:
Chiron Corporation
International Classes:
C12N15/09; A61K39/395; A61K45/00; A61P1/04; A61P9/00; A61P11/00; A61P11/06; A61P25/00; A61P29/00; A61P31/00; A61P31/04; A61P35/00; A61P37/02; A61P37/08; A61P43/00; C07K14/705; C07K16/28; C12N15/12; C12Q1/02; G01N33/15; G01N33/50; G01N33/53; G01N33/566; (IPC1-7): C07K16/28; C07K14/705; C12N15/09; C12Q1/02
Foreign References:
| WO1998050547A2 | 1998-11-12 | |||
| WO1998050547A2 | 1998-11-12 |
Other References:
JPN5002020431, ＹＯＳＨＩＤＡ Ｉ, ＡＣＴＡ ＶＩＲＯＬＯＧＩＣＡ, 199208, Ｖ３６, Ｐ３４７−３５８, CS, ＡＣＡＤＥＭＩＡ ＰＲＡＧＵＥ
JPN5002020433, ＱＵＲＥＳＨＩ Ｓ Ｔ, ＪＯＵＲＮＡＬ ＯＦ ＥＸＰＥＲＩＭＥＮＴＡＬ ＭＥＤＩＣＩＮＥ, 19990215, Ｖ１８９ Ｎ４, Ｐ６１５−６２５, JP
JPN5002020433, ＱＵＲＥＳＨＩ Ｓ Ｔ, ＪＯＵＲＮＡＬ ＯＦ ＥＸＰＥＲＩＭＥＮＴＡＬ ＭＥＤＩＣＩＮＥ, 19990215, Ｖ１８９ Ｎ４, Ｐ６１５−６２５, JP
Attorney, Agent or Firm:
Shusaku Yamamoto (2 outside)
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