Title:
【発明の名称】置換5-ベンジル-2,4-ジアミノピリミジン
Document Type and Number:
Japanese Patent JP2003516320
Kind Code:
A
Abstract:
The invention relates to substituted 5-benzyl-2,4-diaminopyrimidines of general formula (A)wherein R<1 >is C2-C3 alkyl an R<2 >is heterocyclyl, phenyl or naphthyl, bonded by one of its C-atoms and R<3 >is C2-C6 alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, heterocyclylalkyl, alkylsulfonyl, cycloalkylsulfonyl, cycloalkylalkylsulfamoyl, heterocyclysylfonyl, heterocyclylalkylsulfonyl or dialkylsulfamoyl; wherein alkyl, cycloalkyl and alyenyl can carry up to 6 carbon atoms alone or in compositions and can carry up to 6 ring members heterocyclically, alone, or in compositions and the groups R<2 >and R<3 >can be substituted; and to acid addition salts of compounds. The invention also relates to a method for producing the above 5-benzyl-2,4-diaminopyrimidines, to the intermediate. products that are produced, to corresponding medicaments and to the use of 5-benzyl-2,4-diaminopyrimidines as medicinal preparations. The products have antibiotic properties and are useful for combating or preventing infectious diseases.
More Like This:
Inventors:
Gerry, Philip
Mall, peter
Murell, Marc
Muller, Werner
Priller, Philip
Mall, peter
Murell, Marc
Muller, Werner
Priller, Philip
Application Number:
JP2001534784A
Publication Date:
May 13, 2003
Filing Date:
October 27, 2000
Export Citation:
Assignee:
Basilia Farma Sutika AG
International Classes:
A61K31/505; A61K31/506; A61K31/5377; A61K31/538; A61P31/00; A61P31/04; A61P43/00; C07D239/48; C07D239/49; C07D401/10; C07D401/12; C07D403/10; C07D405/10; C07D405/12; C07D409/10; C07D409/12; C07D413/10; C07D417/12; (IPC1-7): C07D239/49; A61K31/505; A61K31/506; A61K31/5377; A61K31/538; A61P31/00; A61P31/04; A61P43/00; C07D401/10; C07D401/12; C07D403/10; C07D405/10; C07D405/12; C07D409/10; C07D409/12; C07D413/10; C07D417/12
Attorney, Agent or Firm:
Hajime Tsukuni (1 person outside)