Title:
【発明の名称】異種タンパク質の安定かつ高収量の発現を容易にするための、Mycobacteriumtuberculosisをコードする配列を使用する方法
Document Type and Number:
Japanese Patent JP2003527830
Kind Code:
A
Abstract:
The present invention relates generally to nucleic acid and amino acid sequences of a fusion polypeptide comprising a Mycobacterium tuberculosis polypeptide, and a heterologous polypeptide of interest, expression vectors and host cells comprising such nucleic acids, and methods for producing such fusion polypeptides. In particular, the invention relates to materials and methods of using such M. tuberculosis sequence as a fusion partner to facilitate the stable and high yield expression of recombinant heterologous polypeptides of both eukaryotic and prokaryotic origin.
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Inventors:
Sukekii, Yasar
Jeffrey Guderian
Jeffrey Guderian
Application Number:
JP2001528556A
Publication Date:
September 24, 2003
Filing Date:
October 06, 2000
Export Citation:
Assignee:
Corixa Corporation
International Classes:
C12N15/09; C07K14/35; C07K14/47; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02; C12P21/04; (IPC1-7): C12N15/09; C07K14/35; C07K19/00; C12N1/15; C12N1/19; C12N1/21; C12N5/10; C12P21/02
Attorney, Agent or Firm:
Shusaku Yamamoto