Title:
超音波造影剤およびその製造方法
Document Type and Number:
Japanese Patent JP2006520754
Kind Code:
A
Abstract:
Method for preparing a lyophilized matrix and, upon reconstitution of the same, a respective injectable contrast agent comprising a liquid aqueous suspension of gas-filled microbubbles stabilized predominantly by a phospholipid. The method comprises preparing an emulsion from an aqueous medium, a phospholipid and a water immiscible organic solvent. The emulsion is then freeze-dried and subsequently reconstituted in an aqueous suspension of gas-filled microbubbles. The method allows to obtain suspensions comprising microbubbles having a relatively small diameter and a narrow size distribution.
More Like This:
| JP5429736 | Tight junction modifier |
| JP2015502334 | How to form particulates of API |
| JPH11506730 | Title of Invention Peptide / Protein Suspension Formulation |
Inventors:
Michelle Schneider
Philip Bussa
Feng Yang
Christian Guyo
Philip Bussa
Feng Yang
Christian Guyo
Application Number:
JP2006502384A
Publication Date:
September 14, 2006
Filing Date:
February 03, 2004
Export Citation:
Assignee:
Blackco International Besloten Fuennaught Shap
International Classes:
A61K9/10; A61B8/00; A61K9/19; A61K47/02; A61K47/06; A61K47/08; A61K47/10; A61K47/12; A61K47/14; A61K47/18; A61K47/20; A61K47/22; A61K47/24; A61K47/26; A61K47/28; A61K47/30; A61K47/34; A61K47/36; A61K47/44; A61K49/00; A61K49/18; A61K49/22
Domestic Patent References:
| JP2000506122A | 2000-05-23 | |||
| JPH05502675A | 1993-05-13 | |||
| JP2005263804A | 2005-09-29 | |||
| JP2002509121A | 2002-03-26 | |||
| JP2001515055A | 2001-09-18 | |||
| JP2000517296A | 2000-12-26 | |||
| JPH1171265A | 1999-03-16 | |||
| JPH09510204A | 1997-10-14 | |||
| JPH09501164A | 1997-02-04 | |||
| JPH07503254A | 1995-04-06 | |||
| JPH04506670A | 1992-11-19 |
Attorney, Agent or Firm:
Kyousei Tamura
Minato Saito
Nagatoshi Shinagawa
Minato Saito
Nagatoshi Shinagawa