Title:
最適化Fc変異体およびそれらの生成方法
Document Type and Number:
Japanese Patent JP2007525443
Kind Code:
A
Abstract:
The present invention relates to optimized Fc variants, methods for their generation, and antibodies and Fc fusions comprising optimized Fc variants.
Inventors:
Gregory Alan Rother
Arthur Jay Chillino
Dun Way
John Rudolph Deathger Wraith
Steven Cole Doverstein
Robert jay haze
Shah Bahadur Khaki
Omid Buffa
Arthur Jay Chillino
Dun Way
John Rudolph Deathger Wraith
Steven Cole Doverstein
Robert jay haze
Shah Bahadur Khaki
Omid Buffa
Application Number:
JP2006509342A
Publication Date:
September 06, 2007
Filing Date:
March 26, 2004
Export Citation:
Assignee:
Zenko Incorporated
International Classes:
C07K16/18; C07K16/00; C07K16/28; C07K16/32; C07K19/00; G16B30/10; C12N15/09; G16B15/20
Domestic Patent References:
| JP2003512019A | 2003-04-02 | |||
| JP2006512407A | 2006-04-13 | |||
| JP2006500009A | 2006-01-05 | |||
| JP2006524039A | 2006-10-26 |
Other References:
CHAPPEL M SUZANNE, THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. V268 N33, JPN5006006054, 1993, pages 25124 - 25131, ISSN: 0001187364
NATURE, vol. 332, JPN6008059253, 1988, pages 563 - 564, ISSN: 0001187365
SHIELDS R L, THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. V276 N9, JPN5006006051, 2 March 2001 (2001-03-02), US, pages 6591 - 6604, ISSN: 0001187366
JEFFERIS ROY, IMMUNOLOGY LETTERS, vol. V82 N. 1 - 2, JPN5006006055, 3 June 2002 (2002-06-03), pages 57 - 65, ISSN: 0001187367
NATURE, vol. 332, JPN6008059253, 1988, pages 563 - 564, ISSN: 0001187365
SHIELDS R L, THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. V276 N9, JPN5006006051, 2 March 2001 (2001-03-02), US, pages 6591 - 6604, ISSN: 0001187366
JEFFERIS ROY, IMMUNOLOGY LETTERS, vol. V82 N. 1 - 2, JPN5006006055, 3 June 2002 (2002-06-03), pages 57 - 65, ISSN: 0001187367
Attorney, Agent or Firm:
Aoyama Aoi
Mitsutaka Iwasaki
Shoji Nakajima
Mitsutaka Iwasaki
Shoji Nakajima