Title:
片頭痛の治療用ヘテロ環式CGRPアンタゴニスト
Document Type and Number:
Japanese Patent JP2007530701
Kind Code:
A
Abstract:
The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their use in therapy for treatment of neurogenic vasodilation, neurogenic inflammation, migraine and other headaches, thermal injury, circulatory shock, flushing associated with menopause, airway inflammatory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), and other conditions the treatment of which can be effected by the antagonism of CGRP-receptors.
Inventors:
Andrew P. Degunan
Han Xiao Jun
Gene M. Devotive
John E. Macaw
Han Xiao Jun
Gene M. Devotive
John E. Macaw
Application Number:
JP2007506432A
Publication Date:
November 01, 2007
Filing Date:
March 28, 2005
Export Citation:
Assignee:
BRISTOL-MYERS SQUIBB COMPANY
International Classes:
C07D401/14; A61K31/4709; A61K31/506; A61K31/517; A61P25/06; A61K31/496
Attorney, Agent or Firm:
Kyousei Tamura
Minato Saito
Nagatoshi Shinagawa
Minato Saito
Nagatoshi Shinagawa