Title:
抗炎症剤
Document Type and Number:
Japanese Patent JP2008543821
Kind Code:
A
Abstract:
The invention provides compounds, pharmaceutical compositions and uses of compounds and salts thereof of general formula (I), for the preparation of a medicament for treatment of an inflammatory disorder, but excluding (S)-3-(1′-methylcyclohexylcarbonylamino)-caprolactam: wherein z is 1, 2, 3 or 4; A is —CO— or —SO2—; Q is linear or branched alkyl, alkenyl, alkynyl, alkoxy, oxyalkyl, aminoalkyl, alkylamino, alklylaminoalkyl, haloalkyl, aryl or substituted aryl; T1 and T2 together constitute a cycloalkyl, cycloalkenyl or polycycloalkyl radical composed of n additional carbon atoms, where n is between 2 and 7; and each hydrogen atom bonded to the carbon atoms in the ring generated by T1 and T2 may be independently be substituted by a group R1, where R1 is independently selected from an alkyl, haloalkyl, alkoxy, haloalkoxy, alkenyl, alkynyl or alkylamino radical of 1 to 20 carbon atoms; or each R1 is independently selected from fluoro, chloro, bromo, iodo, hydroxy, oxyalkyl, amino, aminoalkyl or aminodialkyl radical.
Inventors:
Granger, David John
Fox, david john
Fox, david john
Application Number:
JP2008516413A
Publication Date:
December 04, 2008
Filing Date:
June 14, 2006
Export Citation:
Assignee:
Cambridge Enterprise Limited
International Classes:
A61K31/4015; A61K31/45; A61K31/55; A61P9/00; A61P11/06; A61P17/06; A61P19/02; A61P19/10; A61P25/00; A61P25/28; A61P29/00; A61P31/12; A61P33/00; A61P35/00; A61P37/06; C07D207/273; C07D211/74; C07D223/12
Domestic Patent References:
| JP2008543822A | 2008-12-04 |
Other References:
JPN6012029286; Ｊ Ｍｅｄ Ｃｈｅｍ ４８, 200501, ｐ．８６７-８７４
JPN6012029286; Ｊ Ｍｅｄ Ｃｈｅｍ ４８, 200501, ｐ．８６７-８７４
JPN6012029286; Ｊ Ｍｅｄ Ｃｈｅｍ ４８, 200501, ｐ．８６７-８７４
Attorney, Agent or Firm:
Atsushi Aoki
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Kazumi Nakamura
Takashi Ishida
Fukumoto product
Tetsuji Koga
Kazuhiro Nakamura
Yoichi Watanabe
Kazumi Nakamura