非受容体型チロシンキナーゼのTECファミリーの阻害剤として有用な3,5-二置換ピリド-2-オン

Japanese Patent JP2009507790

A

The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.

WO/2005/028441	CINNAMOYL DERIVATIVES AND USE THEREOF
JP4800936	Use to prepare a combination product comprising an antagonist or inverse agonist of the histamine receptor H3 and an antibiotic psychotic or antidepressant, as well as a pharmaceutical to prevent the adverse effects of those antipsychotics.
WO/2019/218024	PAIN TREATING COMPOUNDS AND USES THEREOF

Charlier, Jean-Damien
Ramayana, Sharn
Durant, Stephen
Jimenez, Juan-Miguel
Gorek, Julian M. C.
Mortymore, Michael

JP2008529133A

February 26, 2009

August 25, 2006

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VERTEX PHARMACEUTICALS INCORPORATED

A61K31/4412; C07D213/64; A61K31/4545; A61K31/496; A61K31/497; A61K31/506; A61P1/00; A61P1/18; A61P3/10; A61P5/14; A61P9/00; A61P9/08; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P13/12; A61P17/00; A61P17/02; A61P17/04; A61P17/06; A61P17/14; A61P19/02; A61P21/04; A61P25/00; A61P27/02; A61P29/00; A61P31/18; A61P35/00; A61P37/02; A61P37/08; A61P43/00; C07D401/04; C07D401/14; C07D471/04

JP2004534010A	2004-11-11
JPH04253961A	1992-09-09
JPH05170740A	1993-07-09
JP2002371078A	2002-12-26
JP2004509867A	2004-04-02
JP2007531752A	2007-11-08

WO2001096308A1	2001-12-20
WO2005097750A1	2005-10-20
WO2006065946A1	2006-06-22
WO2005018557A2	2005-03-03
WO2003068230A1	2003-08-21
WO2003047577A2	2003-06-12

Hidesaku Yamamoto
Takaaki Yasumura
Natsuki Morishita

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