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Document Type and Number:
Japanese Patent JP2010501599
Kind Code:
Vaccine compositions comprising isolated Salmonella spp. cell culture supernatant for the prevention and treatment of Salmonella spp. infection are provided. The culture supernatant is produced under Salmonella pathogenicity island 2 (SPI-2) inducing conditions by incubating Salmonella spp. cells in a low phosphate and low magnesium medium (LPM). Methods for reducing colonization and shedding of Salmonella spp. in a subject by administration of the vaccine compositions are also provided.

Finley, Brett Bee.
Brian Combs
Lee, Eurin
Andrew, Potter
Application Number:
Publication Date:
January 21, 2010
Filing Date:
August 31, 2007
Export Citation:
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The University of British Columbia
University of Saskatchewan as Represented by Bakshin and Infectious Diseases Organization
International Classes:
A61K39/112; A61K39/39; A61P31/04
Attorney, Agent or Firm:
Shusaku Yamamoto
Takamura Yasumura
Morishita Natsuki