Title:
第四級4,5‐エポキシ‐モルフィナン類似体の合成およびそれらのN‐立体異性体の単離のためのプロセス
Document Type and Number:
Japanese Patent JP2010510318
Kind Code:
A
Abstract:
Methods for the synthesis of 4,5-epoxy-morphinaniums using dimethyl formamide and resolution of the diastereomeric products by means of HPLC.
Inventors:
Perez, Julio
Han, Akimui
Abby, Alfred A
Han, Akimui
Abby, Alfred A
Application Number:
JP2009538469A
Publication Date:
April 02, 2010
Filing Date:
November 19, 2007
Export Citation:
Assignee:
Progenics Pharmaceuticals Inc.
International Classes:
C07D489/06; A61K31/485; A61P23/00; A61P25/00; A61P29/00; A61P43/00
Attorney, Agent or Firm:
Warren G. Simor