Title:
CRYSTALLINE FORMS OF BRUTON'S TYROSINE KINASE INHIBITOR
Document Type and Number:
Japanese Patent JP2018048182
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide novel crystalline forms of 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one.SOLUTION: A crystalline form has an X-ray powder diffraction (XRPD) pattern with characteristic peaks at 5.2±0.1° 2-theta, 10.2±0.1° 2-theta, and 20.8±0.1° 2-theta.SELECTED DRAWING: Figure 1
Inventors:
MARK SMYTH
ERICK GOLDMAN
DAVID D WIRTH
NORBERT PURRO
ERICK GOLDMAN
DAVID D WIRTH
NORBERT PURRO
Application Number:
JP2017207591A
Publication Date:
March 29, 2018
Filing Date:
October 26, 2017
Export Citation:
Assignee:
PHARMACYLICS LLC
International Classes:
C07D487/04; A61K31/519; A61P7/02; A61P29/00; A61P35/00; A61P35/02; A61P37/02; A61P37/06; A61P43/00
Domestic Patent References:
| JP2015518885A | 2015-07-06 | |||
| JP2010504324A | 2010-02-12 |
Other References:
平山令明編, 有機化合物結晶作製ハンドブック −原理とノウハウ−, JPN6011053065, 25 July 2008 (2008-07-25), pages 57 - 84, ISSN: 0004024845
高田則幸: "創薬段階における原薬Formスクリーニングと選択", PHARM STAGE, vol. 6, no. 10, JPN6009053755, 15 January 2007 (2007-01-15), pages 20 - 25, ISSN: 0004024846
高田則幸: "創薬段階における原薬Formスクリーニングと選択", PHARM STAGE, vol. 6, no. 10, JPN6009053755, 15 January 2007 (2007-01-15), pages 20 - 25, ISSN: 0004024846
Attorney, Agent or Firm:
Kazuhiro Kiyohara