Title:
【発明の名称】リガンド、そのアンタゴニストまたはアゴニストの効率的な測定のためのハイブリッドリセプターをコードする核酸
Document Type and Number:
Japanese Patent JP2795833
Kind Code:
B2
Abstract:
Hybrid receptors, produced by recombinant DNA technology, comprise (a) the ligand binding domain of a predetermined receptor and (b) a heterologous reporter polypeptide. The hybrid receptors are useful for convenient and large scale assay of biologically active ligands or their antagonists or agonists. (a) may be the extracellular domain of the receptor, or a cytoplasmic domain of a receptor or oncogene. (b) may be an enzyme. A transmembrane domain may be interposed between (a) and (b).
Inventors:
TOOMASU JOSEFU DARU
HEIMO RIIDERU
AKUSERU UURURITSUHI
HEIMO RIIDERU
AKUSERU UURURITSUHI
Application Number:
JP10896196A
Publication Date:
September 10, 1998
Filing Date:
April 30, 1996
Export Citation:
Assignee:
JENENTETSUKU INC
International Classes:
C07H21/04; C07K14/00; C07K14/41; C07K14/415; C07K14/44; C07K14/705; C07K14/71; C07K14/72; C07K19/00; C12N1/21; C12N5/00; C12N5/10; C12N9/00; C12N15/00; C12N15/09; C12P21/00; C12P21/02; C07K14/37; C12Q1/00; G01N33/532; G01N33/566; G01N33/577; G01N33/68; C12R1/19; C12R1/91; (IPC1-7): C12N15/09; C12N1/21; C12N5/10
Domestic Patent References:
| JP60501391A | ||||
| JPS60166699A |
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)