Title:
リーサスD抗原に対して特異性を有する抗原結合性構造を形成し得るポリペプチド、それらをコードするDNA及びその調製方法並びに使用
Document Type and Number:
Japanese Patent JP3841360
Kind Code:
B2
Abstract:
Polypeptides capable of forming antigen binding structures specific for Rhesus D antigens include the sequences indicated in the FIGS. 1 a to 16 b. The obtained polypeptides, being Fab fragments, MAY be used directly as an active ingredient in pharmaceutical and diagnostic compositions. The Fab and their DNA sequences can also be used for the preparation of complete recombinant Anti-Rhesus D antibodies. Useful in pharmaceutical and diagnostic compositions.
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Inventors:
Miescher, Sylvia
Vogel, Monique
Stadler, Beda
Moller, Andreas
Inboden, Martin
Amstutz, Hanspeter
Vogel, Monique
Stadler, Beda
Moller, Andreas
Inboden, Martin
Amstutz, Hanspeter
Application Number:
JP50232398A
Publication Date:
November 01, 2006
Filing Date:
June 20, 1997
Export Citation:
Assignee:
Zet Elbe Belling Akchen Gesell Shaft
International Classes:
C12N15/09; G01N33/53; A61K39/395; A61P7/00; C07K14/00; C07K16/34; C12N15/13; C12N15/62; C12P21/08; G01N33/80; A61K38/00
Foreign References:
WO1991007492A1 | ||||
GB2127434A |
Other References:
J. Immunol. Methods., 1995, Vol.182, pages 7-19
Blood, 1994, Vol.83, pages 2334-44
BioTech., 1993, Vol.11, pages 1145-9
Blood, 1994, Vol.83, pages 2334-44
BioTech., 1993, Vol.11, pages 1145-9
Attorney, Agent or Firm:
Kiyozumi Yazawa
Futachi Kutako
Shohei Oguri
Hironori Honda
Toshimitsu Ichikawa
Takeshi Takamatsu
Futachi Kutako
Shohei Oguri
Hironori Honda
Toshimitsu Ichikawa
Takeshi Takamatsu