Title:
エアゾールを含む麻酔用処方
Document Type and Number:
Japanese Patent JP3911290
Kind Code:
B2
Abstract:
An aerosol formulation of an aerosol propellant and a base form of a narcotic drug selected from the group consisting of fentanyl, sufentanil and remfentanyl is provided. Such a formulation allows for the drug to be dissolved within the propellant and used within a device which does not require the use of a lubricant. Formulations are also disclosed which include lubricants, wherein the lubricant and propellant are both either polar or both non-polar. Thus, the lubricant component does not act as a solvent or cosolvent, but rather acts as a lubricant for the valve used for dispersing the formulation to a patient. Typical non-polar propellants include chlorofluorocarbons, which are typically used in connection with non-polar lubricants such as saturated vegetable oils, e.g. fractionated coconut oils. Typical polar propellants include hydrofluoroalkanes, which are typically used in connection with polar lubricants such as polyethylene glycols.
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Inventors:
Far Stefan Jay.
Lowe Anthony M.
Rubusamend raid
Lowe Anthony M.
Rubusamend raid
Application Number:
JP52972495A
Publication Date:
May 09, 2007
Filing Date:
May 10, 1995
Export Citation:
Assignee:
Aradym Corporation
International Classes:
A61K9/12; A61K31/445; A61K9/00; A61K31/4468; A61K31/4535; A61K47/06; A61P25/04
Domestic Patent References:
| JP2300167A |
Foreign References:
| WO1993011744A1 | ||||
| WO1993011743A1 | ||||
| WO1993005765A1 |
Other References:
Linda L. WEINHOLD, Housing Conditions Influence Acquisition of Sufentanil Aerosol Self-Administration in Rats, Pharmacology Biochemistry and Behavior, 1993年,Vol.44, Pages 141-144
Attorney, Agent or Firm:
Hatsushi Shimizu