Title:
HIV―1感染を阻害するためのケモカイン受容体の使用
Document Type and Number:
Japanese Patent JP4183754
Kind Code:
B2
Abstract:
This invention provides a polypeptide comprising a fragment of a chemokine receptor capable of inhibiting HIV-1 infection. In an embodiment, the chemokine receptor is C-C CKR-5. In another embodiment, the fragment comprises at least one extracellular domain of the chemokine receptor C-C CKR-5. This invention further provides different uses of the chemokine receptor for inhibiting HIV-1 infection.
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Inventors:
All Away, Graham Pea
Drazic, Tatjana
Littwin, Virginia M
Maddon, Paul Jay
Moore, John Pea
Turkey, Alexandra
Drazic, Tatjana
Littwin, Virginia M
Maddon, Paul Jay
Moore, John Pea
Turkey, Alexandra
Application Number:
JP50189598A
Publication Date:
November 19, 2008
Filing Date:
June 13, 1997
Export Citation:
Assignee:
Progenix Pharmaceuticals Inc.
Aaron Diamond AIDS Research Center
Aaron Diamond AIDS Research Center
International Classes:
A01K67/027; C12N15/09; A61K38/00; A61K39/395; A61K45/00; A61K47/48; A61P31/18; A61P43/00; C07K14/16; C07K14/715; C07K16/28; C12N5/10
Foreign References:
| WO1995016789A1 | ||||
| WO1994022477A1 |
Other References:
Biochemistry, 1996年 3月, Vol.35, p3362-3367
Science, 1996年 5月, Vol.272, p872-877
Science, 1996年 5月, Vol.272, p872-877
Attorney, Agent or Firm:
Takehiko Suzue
Sadao Muramatsu
Ryo Hashimoto
Toshio Shirane
Sadao Muramatsu
Ryo Hashimoto
Toshio Shirane