Title:
化学発光増強剤
Document Type and Number:
Japanese Patent JP4434015
Kind Code:
B2
Abstract:
The present invention provides a chemiluminescence enhancer treated to retain favorable dispersibility of fine solid carriers and stably exert a chemiluminescence enhancing action. The invention provides a chemiluminescence enhancer used for signal detection in a solid phase immunoassay using antigen or/and antibody immobilized onto fine solid carriers dispersible in a liquid medium, consisting of a water soluble macromolecular quaternary ammonium salt, a quaternary sulfonium salt or a quaternary phosphonium salt in order to enhance emission of light caused by an enzymatic reaction of a chemiluminescent substrate having dioxetane, wherein the chemiluminescence enhancer is given an aggregation inhibition treatment of the fine solid carriers by the treatment with an oxidizing agent or a reducing agent, and a chemiluminescence method and a kit using the chemiluminescence enhancer.
Inventors:
Moriyama Kazushige
Tetsuji Tanimoto
Tatsuki Matsuno
Yoshihiro Ashihara
Tetsuji Tanimoto
Tatsuki Matsuno
Yoshihiro Ashihara
Application Number:
JP2004515177A
Publication Date:
March 17, 2010
Filing Date:
June 24, 2003
Export Citation:
Assignee:
FUJIREBIO INC.
International Classes:
C09K11/07; G01N21/76; G01N33/532; G01N33/533; G01N33/543; C12Q1/34; C12Q1/42; C12Q1/44
Domestic Patent References:
| JP9507571A | ||||
| JP6009721A | ||||
| JP11322924A |
Attorney, Agent or Firm:
Hajime Tsukuni
Fusayuki Saito
Fusayuki Saito