Title:
組換え型の治療的融合タンパク
Document Type and Number:
Japanese Patent JP4768944
Kind Code:
B2
Abstract:
A recombinant bifunctional fusion protein comprises a first component which is the antigenic ectodomain of measles virus hemagglutinin protein (MeaH) genetically modified not to bind to human cells; and a second component fused thereto which is capable of binding to the surface structure of genetically variable viruses such as HCV or HIV or other therapeutic targets. The second component binds to the target and the first component is recognised by anti-measles antibodies present in the majority of the population. The protein may be used therapeutically to treat HCV or HIV infection or against other therapeutic targets.
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Inventors:
Petrick julie
Application Number:
JP2001535575A
Publication Date:
September 07, 2011
Filing Date:
November 01, 2000
Export Citation:
Assignee:
Troyanis Limited
International Classes:
C12N15/09; A61K39/165; A61K39/21; A61K39/29; A61K45/00; A61P31/12; A61P31/18; C07K14/12; C07K14/47; C07K14/775; C07K16/00; C07K19/00; C12N9/12; C12N15/62; C12P21/08; A61K39/00
Domestic Patent References:
| JPH07509122A | 1995-10-12 |
Attorney, Agent or Firm:
Minoru Nakamura
Fumiaki Otsuka
Sadao Kumakura
Shishido Kaichi
Toshio Imajo
Nobuo Ogawa
Village shrine Atsuo
Takaki Nishijima
Atsushi Hakoda
Fumiaki Otsuka
Sadao Kumakura
Shishido Kaichi
Toshio Imajo
Nobuo Ogawa
Village shrine Atsuo
Takaki Nishijima
Atsushi Hakoda